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Journal ArticleDOI

Concurrent anxiety and substance use disorders among outpatients with major depression: Clinical features and effect on treatment outcome

TLDR
Comorbid anxiety and/or substance use disorder are clinically identifiable, and their presence may define distinct MDD subgroups that have more problems and worse pharmacological treatment outcomes.
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This article is published in Drug and Alcohol Dependence.The article was published on 2009-01-01. It has received 134 citations till now. The article focuses on the topics: Anxiety disorder & Anxiety.

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Citations
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The Diagnosis of Mental Disorders: The Problem of Reification

TL;DR: Based on accreting problems with the current DSM-fourth edition (DSM-IV) classification, it is apparent that validity will not be achieved simply by refining criteria for existing disorders or by the addition of new disorders.
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Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults

TL;DR: Some CAM treatments have evidence of benefit in MDD, however, problems with standardization and safety concerns may limit their applicability in clinical practice.
Journal ArticleDOI

Issues and challenges in the design of culturally adapted evidence-based interventions.

TL;DR: Issues and challenges in the design of cultural adaptations that are developed from an original evidence-based intervention (EBI) are examined and recently emerging multistep frameworks or stage models are examined, as these can systematically guide the development of culturally adapted EBIs.
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The bright side of being blue: depression as an adaptation for analyzing complex problems.

TL;DR: The analytical rumination hypothesis proposes that depression is an evolved response to complex problems, whose function is to minimize disruption and sustain analysis of those problems by giving the triggering problem prioritized access to processing resources.
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Canadian Network for Mood and Anxiety Treatments (CANMAT) clinical guidelines for the management of major depressive disorder in adults. III. Pharmacotherapy.

TL;DR: Second-generation antidepressants are safe, effective and well tolerated treatments for MDD in adults and evidence-based switching and add-on strategies can be used to optimize response in MDD that is inadequately responsive to monotherapy.
References
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Journal ArticleDOI

A rating scale for depression

TL;DR: The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
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Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication

TL;DR: Although mental disorders are widespread, serious cases are concentrated among a relatively small proportion of cases with high comorbidity, as shown in the recently completed US National Comorbidities Survey Replication.
Journal ArticleDOI

Development of a Rating Scale for Primary Depressive Illness

TL;DR: This is an account of further work on a rating scale for depressive states, including a detailed discussion on the general problems of comparing successive samples from a ‘population’, the meaning of factor scores, and the other results obtained.
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The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R).

TL;DR: Notably, major depressive disorder is a common disorder, widely distributed in the population, and usually associated with substantial symptom severity and role impairment, and while the recent increase in treatment is encouraging, inadequate treatment is a serious concern.
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