Journal ArticleDOI
Conditioned place preference from intra-accumbens but not intra-caudate amphetamine injections.
Geoffrey D. Carr,Norman M. White +1 more
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It is suggested that amphetamine-stimulated release of dopamine in nucleus accumbens can increase the incentive value of neutral stimuli with which it is paired, and functional differentiation between different parts of the dopaminergic terminal system is suggested.About:
This article is published in Life Sciences.The article was published on 1983-12-19. It has received 285 citations till now. The article focuses on the topics: Conditioned place preference & Nucleus accumbens.read more
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The reward circuit: linking primate anatomy and human imaging.
Suzanne N. Haber,Brian Knutson +1 more
TL;DR: It is shown that human functional and structural imaging results map increasingly close to primate anatomy, and advances in neuroimaging techniques allow better spatial and temporal resolution.
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The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking
Satoshi Ikemoto,Jaak Panksepp +1 more
TL;DR: The present analysis suggests that NAS DA plays an important role in sensorimotor integrations that facilitate flexible approach responses, and offers the following interpretation for the finding that both conditioned and unconditioned aversive stimuli stimulate DA release in the NAS: NAS DA invigorates approach responses toward 'safety'.
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Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex.
TL;DR: Experiments suggest that dopaminergic neurons localized in the posteromedial ventral tegmental area (VTA) and central linear nucleus raphe selectively project to the ventromedial striatum (medial olfactory tubercle and medial nucleus accumbens shell), whereas the anteromedial VTA has few if any projections to the vents of the ventral striatum.
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Conditioned place preference: What does it add to our preclinical understanding of drug reward?
Michael T. Bardo,Rick A. Bevins +1 more
TL;DR: A theoretical overview of some critical issues relevant to conditioned place preference is provided and it seems clear that CPP measures a learning process that is fundamentally distinct from drug self-administration.
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Addiction, Dopamine, and the Molecular Mechanisms of Memory
Joshua D. Berke,Steven E. Hyman +1 more
TL;DR: This dissertation aims to provide a history of web exceptionalism from 1989 to 2002, a period chosen in order to explore its roots as well as specific cases up to and including the year in which descriptions of “Web 2.0” began to circulate.
References
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Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens.
TL;DR: The hypothesis that non-striatal dopamine may subserve cocaine reward is supported, as several 6-OHDA treated animals displayed a pattern of behaviour resembling extinction, where a high rate of lever pressing was followed by cessation of responding.
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Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity.
TL;DR: D-Amphetamine proved more effective than dopamine in producing locomotor stimulation, whereas both stimulant and depressant effects were observed following injection of apomorphine into the nucleus accumbens.
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Destruction of dopaminergic nerve terminals in nucleus accumbens: effect on d-amphetamine self-administration.
TL;DR: Results suggest that dopaminergic nerve terminals in nucleus accumbens are necessary for both the acquisition and maintenance of d-amphetamine self-administration.