Journal ArticleDOI
Continuous Flow Nitration of Benzaldehyde
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In this article, the nitration of benzaldehyde can be carried out in a safe manner in continuous mode using a microreactor system using a T-micromixer.About:
This article is published in Organic Process Research & Development.The article was published on 2009-08-26. It has received 89 citations till now. The article focuses on the topics: Microreactor.read more
Citations
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Taming hazardous chemistry by continuous flow technology
Marine Movsisyan,Elisabeth Delbeke,Jan Berton,Claudio Battilocchio,Steven V. Ley,Christian V. Stevens +5 more
TL;DR: This review covers some of the latest and most relevant developments in the field of continuous flow chemistry with the focus on hazardous reactions.
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The role of flow in green chemistry and engineering
TL;DR: In this paper, the authors use selected examples to demonstrate how continuous methods of synthesis can be greener than batch synthesis on a small and a large scale, and demonstrate how such methods can help bridge the large gap between academic and industrial settings by often providing a more reproducible, scalable, safe and efficient option for performing chemical reactions.
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Key Green Engineering Research Areas for Sustainable Manufacturing: A Perspective from Pharmaceutical and Fine Chemicals Manufacturers
Concepción Jiménez-González,Peter Poechlauer,Quirinus B. Broxterman,Bing-Shiou Yang,David J. am Ende,James A Baird,Carl Franklin Indianapolis Bertsch,Robert E. Hannah,Phil Dell’Orco,Henk Noorman,Sandy Yee,Raf W.E.G. Reintjens,Andrew S. Wells,Viviane Massonneau,Julie B. Manley +14 more
TL;DR: The American Chemical Society (ACS) Green Chemistry Institute (GCI) and global pharmaceutical companies established the ACS GCI Pharmaceutical Roundtable to encourage the integration of green chemistry and engineering into the pharmaceutical industry as mentioned in this paper.
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Continuous flow synthesis. A pharma perspective.
Laia Malet-Sanz,Flavien Susanne +1 more
The role of flow in green chemistry and engineering
TL;DR: In this review, selected examples are used to demonstrate how continuous methods of synthesis can be greener than batch synthesis on a small and a large scale.
References
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Journal ArticleDOI
Chemistry in microstructured reactors.
TL;DR: This Review aims to address the lack of attention given to microstructured reaction techniques in organic chemistry by providing an overview of the chemistry in microstructures, grouped into liquid-phase, gas- phase, and gas-liquid reactions.
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Multistep continuous-flow microchemical synthesis involving multiple reactions and separations.
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Continuous Flow Reactors, a Tool for the Modern Synthetic Chemist
Charlotte Wiles,Paul Watts +1 more
TL;DR: Microreview as mentioned in this paper focuses on recent developments made in the field of micro reaction technology, highlighting the advantages associated with its use through the synthesis of a diverse array of molecules and highlights the potential of a compound, however, depends not only on structural complexity, but also on the ability to prepare the compound via a scalable synthetic pathway.
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Benchmarking of Microreactor Applications
TL;DR: A bridging function is needed to bring the vast amount of findings documented to a compact format and to compare it to the state of the art in the chemicals-producing industry.
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A New Approach to the Synthesis of 2-Nitrobenzaldehyde. Reactivity and Molecular Structure Studies
TL;DR: In this article, the same acidic heterogeneous catalyst is used for 1,3-dioxolane formation and hydrolysis; it can be recycled several times without loss of efficiency.