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Coronavirus Disease of 2019: a Mimicker of Dengue Infection?

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TLDR
The importance of knowing similar clinical presentations of both coronavirus diseases and why excluding COVID-19 in the differentials in the setting of a pandemic is imprudent are emphasized.
Abstract
At the beginning of 2020, the national health system and medical communities are faced with unprecedented public health challenges. A novel strain of coronavirus, later identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread globally, marking another pandemic of coronaviruses. This viral disease is responsible for devastating pneumonia, named coronavirus disease of 2019 (COVID-19), and projected to persist until the end of the year. In tropical countries, however, concerns arise regarding the similarities of COVID-19 with other infectious diseases due to the same chief complaint, which is fever. One of the infectious disease of a primary concern is dengue infection, which its peak season is approaching. Others report that there are cases of serological cross-reaction of COVID-19 and dengue infection. In this comprehensive review, we underscore the importance of knowing similar clinical presentations of both diseases and emphasize why excluding COVID-19 in the differentials in the setting of a pandemic is imprudent.

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SARS-CoV-2

Jeremy Luban
Journal ArticleDOI

Serological cross-reaction and coinfection of dengue and COVID-19 in Asia: Experience from Indonesia.

TL;DR: This study reported three cases of suspected COVID-19-dengue co-infection in hospitals of Bali, Indonesia and revealed possible cross-reactivity between SARS-CoV-2 and DENV antibodies based on rapid serological tests.
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Development and performance evaluation of a rapid in-house ELISA for retrospective serosurveillance of SARS-CoV-2.

TL;DR: In this paper, a rapid SARS-CoV2 specific ELISA for detection of anti-SARS CoV2 IgG from patients' biological samples was developed and evaluated, which can be applied as one of the early and retrospective seromonitoring tools in all over the affected areas.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
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