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SARS-CoV-2
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The article was published on 2020-01-01 and is currently open access. It has received 1967 citations till now.read more
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Journal ArticleDOI
Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science.
Emily A. Holmes,Emily A. Holmes,Rory C. O'Connor,V. Hugh Perry,Irene Tracey,Simon Wessely,Louise Arseneault,Clive Ballard,Helen Christensen,Roxane Cohen Silver,Ian P. Everall,Tamsin Ford,Ann John,Thomas Kabir,Kate King,Ira Madan,Susan Michie,Andrew K. Przybylski,Roz Shafran,Angela Sweeney,Carol M. Worthman,Lucy Yardley,Katherine Cowan,Claire Cope,Matthew Hotopf,Edward T. Bullmore +25 more
TL;DR: There is an urgent need for research to address how mental health consequences for vulnerable groups can be mitigated under pandemic conditions, and on the impact of repeated media consumption and health messaging around COVID-19.
Journal ArticleDOI
Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review.
W. Joost Wiersinga,Andrew Rhodes,Allen C. Cheng,Sharon J. Peacock,Sharon J. Peacock,Hallie C. Prescott +5 more
TL;DR: This review discusses current evidence regarding the pathophysiology, transmission, diagnosis, and management of COVID-19, the novel severe acute respiratory syndrome coronavirus 2 pandemic that has caused a worldwide sudden and substantial increase in hospitalizations for pneumonia with multiorgan disease.
Journal ArticleDOI
Mild or Moderate Covid-19.
TL;DR: Covid-19 (the illness caused by SARS-CoV-2) has a range of clinical manifestations, including cough, fever, malaise, myalgias, gastrointestinal symptom...
Journal ArticleDOI
Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19.
Wentao Ni,Xiuwen Yang,Deqing Yang,Jing Bao,Ran Li,Yongjiu Xiao,Chang Hou,Haibin Wang,Jie Liu,Donghong Yang,Yu Xu,Zhaolong Cao,Zhancheng Gao +12 more
TL;DR: The SARS-CoV-2 spike glycoprotein, which binds to ACE2, is a potential target for developing specific drugs, antibodies, and vaccines and Restoring the balance between the RAS and ACE2/angiotensin-(1–7)/MAS may help attenuate organ injuries.
Journal ArticleDOI
CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells.
Ke Wang,Wei Chen,Zheng Zhang,Yong-Qiang Deng,Jian-Qi Lian,Peng Du,Ding Wei,Yang Zhang,Xiu-Xuan Sun,Li Gong,Xu Yang,Lei He,Lei Zhang,Zhiwei Yang,Jie-Jie Geng,Ruo Chen,Zhang Hai,Bin Wang,Yu-Meng Zhu,Gang Nan,Jian-Li Jiang,Ling Li,Jiao Wu,Peng Lin,Wan Huang,Liangzhi Xie,Zhaohui Zheng,Kui Zhang,Jinlin Miao,Hong-Yong Cui,Min Huang,Jun Zhang,Ling Fu,Xiang-Min Yang,Zhongpeng Zhao,Shihui Sun,Hongjing Gu,Zhe Wang,Chun-Fu Wang,Yacheng Lu,Liu Yingying,Qing-Yi Wang,Huijie Bian,Ping Zhu,Zhi-Nan Chen +44 more
TL;DR: A novel virus entry route, CD147-spike protein, is revealed, which provides an important target for developing specific and effective drug against COVID-19.
References
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Journal ArticleDOI
Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science.
Emily A. Holmes,Emily A. Holmes,Rory C. O'Connor,V. Hugh Perry,Irene Tracey,Simon Wessely,Louise Arseneault,Clive Ballard,Helen Christensen,Roxane Cohen Silver,Ian P. Everall,Tamsin Ford,Ann John,Thomas Kabir,Kate King,Ira Madan,Susan Michie,Andrew K. Przybylski,Roz Shafran,Angela Sweeney,Carol M. Worthman,Lucy Yardley,Katherine Cowan,Claire Cope,Matthew Hotopf,Edward T. Bullmore +25 more
TL;DR: There is an urgent need for research to address how mental health consequences for vulnerable groups can be mitigated under pandemic conditions, and on the impact of repeated media consumption and health messaging around COVID-19.
Journal ArticleDOI
Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review.
W. Joost Wiersinga,Andrew Rhodes,Allen C. Cheng,Sharon J. Peacock,Sharon J. Peacock,Hallie C. Prescott +5 more
TL;DR: This review discusses current evidence regarding the pathophysiology, transmission, diagnosis, and management of COVID-19, the novel severe acute respiratory syndrome coronavirus 2 pandemic that has caused a worldwide sudden and substantial increase in hospitalizations for pneumonia with multiorgan disease.
Journal ArticleDOI
Mild or Moderate Covid-19.
TL;DR: Covid-19 (the illness caused by SARS-CoV-2) has a range of clinical manifestations, including cough, fever, malaise, myalgias, gastrointestinal symptom...
Journal ArticleDOI
Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19.
Wentao Ni,Xiuwen Yang,Deqing Yang,Jing Bao,Ran Li,Yongjiu Xiao,Chang Hou,Haibin Wang,Jie Liu,Donghong Yang,Yu Xu,Zhaolong Cao,Zhancheng Gao +12 more
TL;DR: The SARS-CoV-2 spike glycoprotein, which binds to ACE2, is a potential target for developing specific drugs, antibodies, and vaccines and Restoring the balance between the RAS and ACE2/angiotensin-(1–7)/MAS may help attenuate organ injuries.
Journal ArticleDOI
CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells.
Ke Wang,Wei Chen,Zheng Zhang,Yong-Qiang Deng,Jian-Qi Lian,Peng Du,Ding Wei,Yang Zhang,Xiu-Xuan Sun,Li Gong,Xu Yang,Lei He,Lei Zhang,Zhiwei Yang,Jie-Jie Geng,Ruo Chen,Zhang Hai,Bin Wang,Yu-Meng Zhu,Gang Nan,Jian-Li Jiang,Ling Li,Jiao Wu,Peng Lin,Wan Huang,Liangzhi Xie,Zhaohui Zheng,Kui Zhang,Jinlin Miao,Hong-Yong Cui,Min Huang,Jun Zhang,Ling Fu,Xiang-Min Yang,Zhongpeng Zhao,Shihui Sun,Hongjing Gu,Zhe Wang,Chun-Fu Wang,Yacheng Lu,Liu Yingying,Qing-Yi Wang,Huijie Bian,Ping Zhu,Zhi-Nan Chen +44 more
TL;DR: A novel virus entry route, CD147-spike protein, is revealed, which provides an important target for developing specific and effective drug against COVID-19.