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Journal ArticleDOI

Cytochrome c oxidase. Towards a clarification of its structure, interactions and mechanism.

Angelo Azzi
- 01 Dec 1980 - 
- Vol. 594, Iss: 4, pp 231-252
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This article is published in Biochimica et Biophysica Acta.The article was published on 1980-12-01. It has received 298 citations till now. The article focuses on the topics: Cytochrome c peroxidase & Cytochrome c oxidase.

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Citations
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Mitochondrial generation of free radicals and hypoxic signaling

TL;DR: Although excess ROS and RNS can lead to oxidative and nitrosative stress, moderate to low levels of both function in cellular signaling pathways, which have important implications for cancer, inflammation and a variety of other diseases.
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Mitochondrial targets of drug toxicity.

TL;DR: The significance is further underscored by the recent identification of bioenergetic control points for cell replication and differentiation and the realization that mitochondria play a determinant role in cell signaling and apoptotic modes of cell death.
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The superfamily of heme-copper respiratory oxidases.

TL;DR: It has been recognized that most of the bacterial oxidases, despite differences in their substrates, oxygen affinities, and heme types and metal compositions, are closely related members of a single superfamily called the heme-copper oxidase superfamily.
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The proton-ATPase of bacteria and mitochondria.

TL;DR: This review is pleased to have had the opportunity to review the field at an opportune time, and expects that the rapid chemical characterization of mutation and reversion sites by DNA sequencing will become possible within the near future, and that site-specific mutagenesis may soon allow us to introduce amino acid substitutions in specific domains of specific subunits.
References
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Journal ArticleDOI

The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis

TL;DR: The results show that the polyacrylamide gel electrophoresis method can be used with great confidence to determine the molecular weights of polypeptide chains for a wide variety of proteins.
Journal ArticleDOI

Chemiosmotic coupling in oxidative and photosynthetic phosphorylation

Peter Mitchell
- 01 Aug 1966 - 
TL;DR: The end result of the coupling between the flows through the o/r and h/d pathways in oxidative phosphorylation in mitochondria is that, for the equivalent of each pair of electrons traversing the respiratory chain, up to 3 anhydro-bond equivalents may normally traverse the h/D pathway from adenosine diphosphate plus inorganic phosphate (ADP +Pi) to water.
BookDOI

The Enzymes of Biological Membranes

TL;DR: Electron Microscopy of Biological Membranes: A Completely Membrane Associated Cytoskeleton and Lipid Polymorphism: Technical Aspects and "Isotropic" Lipid Structures and Lipids.
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Fluorescence Spectroscopy of Proteins

TL;DR: Fluorescence spectroscopy of proteins, analyzing polarity, distances between groups, flexibility and conformational transitions, and its applications in medicine and materials science.
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Proton pump coupled to cytochrome c oxidase in mitochondria.

TL;DR: It is reported here that the redox activity of mitochondrial cytochrome c oxidase is coupled to the translocation of hydrogen ions across the inner mitochondrial membrane, which may be a clue to the role of cy tochrome oxidase in energy conservation.
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