Journal ArticleDOI
Chemiosmotic coupling in oxidative and photosynthetic phosphorylation
TLDR
The end result of the coupling between the flows through the o/r and h/d pathways in oxidative phosphorylation in mitochondria is that, for the equivalent of each pair of electrons traversing the respiratory chain, up to 3 anhydro-bond equivalents may normally traverse the h/D pathway from adenosine diphosphate plus inorganic phosphate (ADP +Pi) to water.Abstract:
50 years ago Peter Mitchell proposed the chemiosmotic hypothesis for which he was awarded the Nobel Prize for Chemistry in 1978. His comprehensive review on chemiosmotic coupling known as the first "Grey Book", has been reprinted here with permission, to offer an electronic record and easy access to this important contribution to the biochemical literature. This remarkable account of Peter Mitchell's ideas originally published in 1966 is a landmark and must-read publication for any scientist in the field of bioenergetics. As far as was possible, the wording and format of the original publication have been retained. Some changes were required for consistency with BBA formats though these do not affect scientific meaning. A scanned version of the original publication is also provided as a downloadable file in Supplementary Information and can be found online at doi:10.1016/j.bbabio.2011.09.018. See also Editorial in this issue by Peter R. Rich. Original title: CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION, by Peter Mitchell, Glynn Research Laboratories, Bodmin, Cornwall, England.read more
Citations
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Journal ArticleDOI
Energy conservation in chemotrophic anaerobic bacteria.
TL;DR: This article corrects the article on p. 100 in vol.
Journal ArticleDOI
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
TL;DR: The mechanism of mitochondrial RIRR highlights the central role of mitochondria-formed ROS, and all of the known ROS-producing sites and their relevance to the mitochondrial ROS production in vivo are discussed.
Journal ArticleDOI
Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria.
TL;DR: The crystal structure of bovine mitochondrial F1-ATPase determined at 2.8 Å resolution supports a catalytic mechanism in intact ATP synthase in which the three catalytic subunits are in different states of the catalytic cycle at any instant.
Journal ArticleDOI
Mimicking photosynthetic solar energy transduction
TL;DR: The overall energy transduction process in the liposomal system mimics the solar energy conversion system of a photosynthetic bacterium and illustrates the advantages of designing functional nanoscale devices based on biological paradigms.
Journal ArticleDOI
Energetics of syntrophic cooperation in methanogenic degradation.
TL;DR: S syntrophically fermenting bacteria synthesize ATP by substrate-level phosphorylation and reinvest part of the ATP-bound energy into reversed electron transport processes, to release the electrons at a redox level accessible by the partner bacteria and to balance their energy budget.
References
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Journal ArticleDOI
Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism
TL;DR: Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism is described.
Book ChapterDOI
The respiratory chain and oxidative phosphorylation.
Britton Chance,G. R. Williams +1 more
TL;DR: How the respiratory chain and oxidative phosphorylation works and which substances may disable it are explained.
Journal ArticleDOI
Partial resolution of the enzymes catalyzing oxidative phosphorylation. I. Purification and properties of soluble dinitrophenol-stimulated adenosine triphosphatase.
Journal ArticleDOI
The microestimation of succinate and the extinction coefficient of cytochrome c.
Journal ArticleDOI
A naturally occurring inhibitor of mitochondrial adenosine triphosphatase.
TL;DR: The purpose of this paper is to describe the purification and properties of a low molecular weight mitochondrial protein which inhibits the soluble ATPase and increases cold activity.