Open AccessJournal Article
Cytoskeleton of mouse embryo fibroblasts. Electron microscopy of platinum replicas.
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TLDR
The cytoskeleton structure of the central (endoplasm) region of the cell was markedly different from that of the lamelloplasm, and sites of microfilament bundle convergence can be visualized near the nucleus after partial removal of the sheath by more complete detergent extraction.About:
This article is published in European Journal of Cell Biology.The article was published on 1984-05-01 and is currently open access. It has received 60 citations till now. The article focuses on the topics: Microfilament & Cytoskeleton.read more
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Journal ArticleDOI
The many faces of actin: matching assembly factors with cellular structures
Ekta Seth Chhabra,Henry N. Higgs +1 more
TL;DR: This work focuses on structures at the plasma membrane, including both sheet-like protrusive structures and finger-like protrusions (such as filopodia and microvilli) and insights gained from studies of adherens junctions and the immunological synapse are considered.
Journal ArticleDOI
Myosin II filament assemblies in the active lamella of fibroblasts: their morphogenesis and role in the formation of actin filament bundles.
TL;DR: It is proposed that zig-zag assemblies of myosin II filaments induce the formation of actin bundles by pulling on an actin filament network and that co-alignment of act in and myosIn filaments proceeds via folding of myOSin II filament assemblies in an accordion-like fashion.
Journal ArticleDOI
Membrane ruffles in cell migration: indicators of inefficient lamellipodia adhesion and compartments of actin filament reorganization.
TL;DR: It is shown here that membrane ruffles differ from the underlying cell lamella by more densely packed bundles of actin filaments that are enriched in the actin cross- linkers filamin and ezrin, pointing to a specific bundling process based on these cross-linkers.
Book ChapterDOI
Correlative light and electron microscopy of the cytoskeleton of cultured cells.
T.M. Svitkina,Gary G. Borisy +1 more
TL;DR: Correlative analysis of the same cells by light and electron microscopy,--that is, high temporal resolution analysis of fluorescent features in a living cell followed by high resolution spatial analysis of structural features in the same cell, provides an opportunity to combine the advantages of both techniques and establish functional connections between cytoskeletal dynamics and supramolecular organization.
Related Papers (5)
Filament organization revealed in platinum replicas of freeze-dried cytoskeletons.
John E. Heuser,Marc W. Kirschner +1 more