Journal ArticleDOI
Δ9-tetrahydrocannabinol alters flow of blood to subcortical areas of the conscious rat brain
Harold Goldman,Harold Goldman,Rose Dagirmanjian,William G. Drew,Sharon E. Murphy,Sharon E. Murphy +5 more
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During the period of cataleptoid behavior at 20 minutes after injection, the flows of blood to dorsal hippocampus, hypothalamus, cerebellum and basal ganglia were reduced significantly, whereas perfusion of cortical areas was unaffected, believed to reflect acute functional responses to Δ9THC.About:
This article is published in Life Sciences.The article was published on 1975-08-01. It has received 23 citations till now.read more
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Journal ArticleDOI
Cannabinoid physiology and pharmacology: 30 years of progress
Allyn C. Howlett,Allyn C. Howlett,Christopher S. Breivogel,Steven R. Childers,Sam A. Deadwyler,Robert E. Hampson,Linda J. Porrino +6 more
TL;DR: Delta9-Tetrahydrocannabinol from Cannabis sativa is mimicked by cannabimimetic analogs such as CP55940 and WIN55212-2, and antagonized by rimonabant and SR144528, through G-protein-coupled receptors, CB1 in the brain, and CB2 in the immune system.
Journal ArticleDOI
Marijuana intoxication and brain activation in marijuana smokers
TL;DR: Behavioral manifestations of marijuana intoxication may be associated with increased functional activity of the brain especially the frontal cortex, insula and cingulate gyrus.
BookDOI
Cannabinoids and the brain
TL;DR: Cannabinoids and the brain / , Cannabinoids andThe brain /, کتابخانه دیجیتال جندی شاپر اهواز
Journal ArticleDOI
Neuroimaging studies of acute effects of THC and CBD in humans and animals: a systematic review.
Albert Batalla,J. A. Crippa,Geraldo F. Busatto,Francisco Silveira Guimarães,Francisco Silveira Guimarães,Antonio Waldo Zuardi,Antonio Waldo Zuardi,Olga Valverde,Zerrin Atakan,Philip McGuire,Sagnik Bhattacharyya,Rocío Martín-Santos,Rocío Martín-Santos +12 more
TL;DR: Functional neuroimaging studies have provided extensive evidence for the acute modulation of brain function by cannabinoids, but further studies are needed in order to understand the neural mechanisms underlying these effects.
Book ChapterDOI
Lipotropin and the central nervous system.
TL;DR: This chapter deals with the interaction of the lipotropin fragments and related peptides with the central nervous system (CNS) and the differences known to exist between the two classes of LPH fragments.
References
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Loss of recent memory after bilateral hippocampal lesions.
TL;DR: The results of these studies point to the importance of the hippocampal complex for normal memory function in patients who had undergone similar, but less radical, bilateral medial temporallobe resections, and as a warning to others of the risk to memory involved in bilateral surgical lesions of the hippocampusal region.
Journal ArticleDOI
Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain.
TL;DR: It is revealed that norepinephrine and dopamine are specifically localized in complex systems of neurons in the brain, a finding which lends support to the hypothesis that both amines may be neurotransmitters in the central nervous system.
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Cerebral blood flow and oxygen consumption in man.
TL;DR: In the present study great emphasis will be put on information regarding cerebral oxygen consumption in man, whereas only scant attention will be paid to the intermediary metabolism of the brain.
Journal ArticleDOI
Connections of the cerebral cortex. I. The albino rat. A. Topography of the cortical areas
Journal ArticleDOI
Regional blood flow by fractional distribution of indicators.
TL;DR: K42 Cl, Rb86Cl and iodoantipyrine were given in single intravenous injections to rats and the isotope content of the organs and the arterial blood concentrations were studied as a function of isotopes.