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Diagnosis and Treatment of Diabetic Foot Infections

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TLDR
Foot infections in patients with diabetes cause substantial morbidity and frequent visits to health care professionals and may lead to amputation of a lower extremity and, thus, the urgency and venue of management.
Abstract
Benjamin A. Lipsky, Anthony R. Berendt, H. Gunner Deery, John M. Embil, Warren S. Joseph, Adolf W. Karchmer, Jack L. LeFrock, Daniel P. Lew, Jon T. Mader, Carl Norden, and James S. Tan Medical Service, Veterans Affairs Puget Sound Health Care System, and Division of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, Washington; Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Northern Michigan Infectious Diseases, Petoskey, Michigan; Section of Infectious Diseases, Department of Medicine, University of Manitoba, Winnipeg, Manitoba; Section of Podiatry, Department of Primary Care, Veterans Affairs Medical Center, Coatesville, Pennsylvania; Division of Infectious Diseases, Department of Medicine, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, Massachusetts; Dimensional Dosing Systems, Sarasota, Florida; Department of Medicine, Service of Infectious Diseases, University of Geneva Hospitals, Geneva, Switzerland; Department of Internal Medicine, The Marine Biomedical Institute, and Department of Orthopaedics and Rehabilitation, University of Texas Medical Branch, Galveston, Texas; Department of Medicine, New Jersey School of Medicine and Dentistry, and Cooper Hospital, Camden, New Jersey; and Department of Internal Medicine, Summa Health System, and Northeastern Ohio Universities College of Medicine, Akron, Ohio

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Journal ArticleDOI

The Diabetic Foot

TL;DR: The natural history of the diabetic foot is reviewed and the surgical impact of the Infectious Diseases Society of America clinical practice guideline- based care of diabetic foot infections is assessed.
Journal ArticleDOI

Diabetic Foot Disorders: A Clinical Practice Guideline (2006 Revision)

TL;DR: A clinical practice guideline for diabetic foot disorders is presented based on currently available evidence, committee consensus, and current clinical practice and provides evidence-based guidance for general patterns of practice.
Journal ArticleDOI

Common infections in diabetes: pathogenesis, management and relationship to glycaemic control.

TL;DR: Further research is needed to improve the understanding of the role of diabetes and glycaemic control in the pathogenesis and management of community‐ and hospital‐acquired infections.
Journal ArticleDOI

Treatment for diabetic foot ulcers

TL;DR: People with diabetes develop foot ulcers because of neuropathy (sensory, motor, and autonomic deficits), ischaemia, or both and appropriate education for patients, the provision of posthealing footwear, and regular foot care can reduce rates of re-ulceration.
References
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Journal ArticleDOI

Wound microbiology and associated approaches to wound management.

TL;DR: A detailed analysis of wound microbiology, together with current opinion and controversies regarding wound assessment and treatment, has attempted to capture and address microbiological aspects that are critical to the successful management of microorganisms in wounds.
Journal ArticleDOI

Pathways to Diabetic Limb Amputation: Basis for Prevention

TL;DR: Defining causal pathways that predispose to diabetic limb amputation suggests practical interventions that may be effective in preventing diabetic limb loss.
Journal ArticleDOI

Wound bed preparation: a systematic approach to wound management.

TL;DR: Wound bed preparation is the management of a wound in order to accelerate endogenous healing or to facilitate the effectiveness of other therapeutic measures to select the most appropriate intervention.
Journal ArticleDOI

Immune dysfunction in patients with diabetes mellitus (DM)

TL;DR: Patients with diabetes mellitus (DM) have infections more often than those without DM and an increased adherence of microorganisms to diabetic compared to nondiabetic cells has been described for Candida albicans.
Journal ArticleDOI

Incidence, outcomes, and cost of foot ulcers in patients with diabetes.

TL;DR: The results appear to support the value of foot-ulcer prevention programs for patients with diabetes and the attributable cost of care compared with that in patients without foot ulcers.
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