Journal ArticleDOI
Diastereoselective Ireland-Claisen rearrangement of allylic alcohols
Jin K. Cha,S.C. Lewis +1 more
TLDR
In this paper, the Ireland-Claisen rearrangement of allylic glycolate esters is described in which the stereocontrol of the prochiral sp 2 sites is achieved by the allylic oxygen substitutent.About:
This article is published in Tetrahedron Letters.The article was published on 1984-01-01. It has received 47 citations till now. The article focuses on the topics: Claisen rearrangement & Ireland–Claisen rearrangement.read more
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Journal ArticleDOI
Selective Synthesis by Use of Lewis Acids in the Presence of Organocopper and Related Reagents. New Synthetic Methods (61)
TL;DR: In this paper, it was shown that the two species cannot coexist and undergo transmetalation reactions at low temperature, but they exhibit new and unique reactivities and selectivities: in conjugate additions, e.g., not only activation but also high regio-, stereo-, and chemo-selectivity as well as very high asymmetric induction.
Journal ArticleDOI
New aspects of the Ireland and related Claisen rearrangements
Book ChapterDOI
7.2 – Claisen Rearrangements
TL;DR: In this paper, a survey of variants of the Claisen rearrangement that are of general use in stereoselective organic synthesis is presented, highlighting the influence of steric and electronic parameters on transition state geometries.
Reference EntryDOI
Organocopper Reagents: Substitution, Conjugate Addition, Carbo/Metallocupration, and Other Reactions
TL;DR: In this paper, two reviews were contributed to the Organic Reactions series covering substitution and conjugate addition reactions in organocopper chemistry, and many solutions to this problem now exist.
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Journal ArticleDOI
Kinetic resolution of racemic allylic alcohols by enantioselective epoxidation. A route to substances of absolute enantiomeric purity
Víctor S. Martín,Scott S. Woodard,Tsutomu Katsuki,Yasuhiro Yamada,Masonari Ikeda,K. Barry Sharpless +5 more
Journal ArticleDOI
Stereocontrol in the synthesis of acyclic systems: applications to natural product synthesis
Journal ArticleDOI