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Dietary Supplements: Regulatory Challenges and Research Resources.

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TLDR
A case study of research at the Office of Dietary Supplements at the National Institutes of Health, USA is provided, along with some resources it has developed that are available to all scientists.
Abstract
Many of the scientific and regulatory challenges that exist in research on the safety, quality and efficacy of dietary supplements are common to all countries as the marketplace for them becomes increasingly global. This article summarizes some of the challenges in supplement science and provides a case study of research at the Office of Dietary Supplements at the National Institutes of Health, USA, along with some resources it has developed that are available to all scientists. It includes examples of some of the regulatory challenges faced and some resources for those who wish to learn more about them.

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Food-Derived Bioactive Peptides in Human Health: Challenges and Opportunities.

TL;DR: The current techniques, challenges of the currentBioactive peptide production techniques, the oral use and gastrointestinal bioavailability of these food-derived bioactive peptides, and the overall regulatory environment are discussed.
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From pharmaceuticals to nutraceuticals: bridging disease prevention and management.

TL;DR: The understanding of the potential mechanisms of action of pharmaceutically active substances contained in nutraceuticals that may improve health and reduce the risk of pathological conditions while enhancing overall well-being is the challenge for nutr pharmaceuticals to be considered as a preventive and therapeutic efficient tool in facing some diseases.
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Vitamin D microencapsulation and fortification: Trends and technologies

TL;DR: The present review is an undate on Vit D, in light of its fortification level, RDA, factors affecting its bioavailability and various microencapsulation techniques adopted to develop Vit D-nanomaterials and their fate in food fortification.
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Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents.

TL;DR: The aim of this article is to review the role of platelets and the relationship between their structure, function, and the interactions of their constituents in systemic inflammation and atherosclerosis to primary prevention of CVD.
References
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Journal ArticleDOI

Biomarkers of Nutrition for Development (BOND)-Iron Review.

TL;DR: A full appreciation of folate's history as a public health issue, its biology, and an overview of available biomarkers and their interpretation across a range of clinical and population-based uses are provided.
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Why US Adults Use Dietary Supplements

TL;DR: The most commonlyreported reasons for using supplements were to improve or maintain overall health as discussed by the authors, while supplement users are more likely to report very good or excellent health, have health insurance, use alcohol moderately, eschew cigarette smoking, and exercise more frequently than nonusers.
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Reporting randomized, controlled trials of herbal interventions: an elaborated CONSORT statement

TL;DR: This study elaborated on the 22-item checklist of the Consolidated Standards of Reporting Trials (CONSORT) statement to help authors and editors improve reporting of RCTs of herbal interventions and emphasized minimizing item elaborations and additions and basing elaborations on evidence whenever possible.
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Trends in Dietary Supplement Use Among US Adults From 1999-2012.

TL;DR: Overall use of dietary supplements remained stable from 1999-2012, use of MVMM decreased, and trends in use of individual supplements varied and were heterogeneous by population subgroups.
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Update on NHANES Dietary Data: Focus on Collection, Release, Analytical Considerations, and Uses to Inform Public Policy.

TL;DR: Dietary data are used to describe intake of foods, nutrients, food groups, and dietary patterns by the US population and large sociodemographic groups to plan and evaluate nutrition programs and policies and the strengths and limitations of these data are discussed.
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