Journal ArticleDOI
Differences in phosphorylation state of neurofilament proteins in ganglionic and aganglionic bowel segments of children with Hirschsprung's disease.
Th.M. Luider,Th.M. Luider,M.W. van Dommelen,M.W. van Dommelen,D. Tibboel,D. Tibboel,J.H.C. Meijers,J.H.C. Meijers,F.J.W. ten Kate,F.J.W. ten Kate,John Q. Trojanowski,John Q. Trojanowski,J.C. Molenaar,J.C. Molenaar +13 more
Reads0
Chats0
TLDR
It is surmise that during the ingrowth and differentiation of hypertrophic axons the composition of neurofilament proteins formed in the aganglionic bowel segment differs from the neuro Filament proteins form in the ganglionic and control bowel segments.About:
This article is published in Journal of Pediatric Surgery.The article was published on 1992-07-01. It has received 13 citations till now. The article focuses on the topics: Neurofilament & Hirschsprung's disease.read more
Citations
More filters
Journal ArticleDOI
Retinal Ganglion Cells Downregulate Gene Expression and Lose Their Axons within the Optic Nerve Head in a Mouse Glaucoma Model
Ileana Soto,Ileana Soto,Ericka N. Oglesby,Brian Buckingham,Janice L. Son,Elisha D.O. Roberson,Elisha D.O. Roberson,Michael R. Steele,Denise M. Inman,Monica L. Vetter,Philip J. Horner,Nicholas Marsh-Armstrong +11 more
TL;DR: The data support the view that RGC degeneration in glaucoma has two separable stages: the first involves atrophy of RGCs, whereas the second involves an insult to axons, which causes the degeneration of axon portions distal to the optic nerve head but does not cause the immediate degenerations of intraretinal portions of axons.
Journal ArticleDOI
Diagnosis of Hirschsprung's disease: a prospective, comparative accuracy study of common tests.
Fleur de Lorijn,Johannes B. Reitsma,Wieger Voskuijl,Daniel C. Aronson,Fiebo J W ten Kate,Anne M.J.B. Smets,Jan A.J.M. Taminiau,Marc A. Benninga +7 more
TL;DR: RSB is the most accurate test for diagnosing HD, and it has the lowest rate of inconclusive test results.
Journal ArticleDOI
Implications of intermediate filament protein phosphorylation.
TL;DR: Intermediate filament (IF) proteins, a large family of tissue specific proteins, undergo several posttranslational modifications, with phosphorylation being the most studied modification.
Journal ArticleDOI
Immunohistochemical markers for quantitative studies of neurons and glia in human neocortex.
TL;DR: Improved preservation of NeuN and CNPase staining, and full preservation of GFAP and CD45/LCA staining in tissue fixed by perfusion and stored for up to 3 years in 0.1% paraformaldehyde solution at 4C, indicated that immunohistochemistry can be performed in well-preserved biobank material.
Journal ArticleDOI
Visceral neuropathy in slow transit constipation: an immunohistochemical investigation with monoclonal antibodies against neurofilament.
W. R. Schouten,Fibo J. W. ten Kate,Eelco J. R. de Graaf,Ericus C. A. M. Gilberts,Jaap L. Simons,P. Klück +5 more
TL;DR: Findings indicate that a visceral neuropathy seems to be present in the majority of patients with severe, so-called idiopathic slow transit constipation.
References
More filters
Journal ArticleDOI
A "direct-coloring" thiocholine method for cholinesterases
Morris J. Karnovsky,Logan Roots +1 more
TL;DR: Colour is prooduced directly at the site of eoozyusuatic activity, facilitating estinsation of h.hue ooptinuuius imscusi)soti000s tinse; the l)necipitate is finselv grssusuulan, so) lhooot, eveos witis prolonged incusbosoh booms, needle-like deposits are not ob)served; instemuse cnol(on s
MonographDOI
The neural crest
TL;DR: The Neural Crest is a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life as discussed by the authors, and the ontogeny of the neural crest embodies the most important issues in developmental biology.
Journal ArticleDOI
Two-stage expression of neurofilament polypeptides during rat neurogenesis with early establishment of adult phosphorylation patterns
TL;DR: Results show that sequential forms of NFs, composed of NF-M and NF-L, appears to function in establishing the neuronal phenotype and in initiating and maintaining neurite outgrowth, and a “mature” state to the NF is expressed by developing and maturing neurons throughout the nervous system.
Journal Article
A genetic study of Hirschsprung disease
TL;DR: A model of gene action with random effects during morphogenesis is compatible with observations, and an increased sex ratio and an elevated risk to sibs are observed.
Related Papers (5)
An immunohistochemical study of the enteric neural plexi in Hirschsprung's disease.
J. M. Mackenzie,Michael F. Dixon +1 more