Open AccessJournal Article
Direct stimulation of the adrenal cortex by interleukin-1.
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TLDR
IL-1 increases rat serum corticosterone levels, IL-1 directly stimulates the adrenal cortex, and the stimulation may be mediated through prostaglandin synthesis.About:
This article is published in Surgery.The article was published on 1987-08-01 and is currently open access. It has received 128 citations till now. The article focuses on the topics: Corticosterone & Adrenal cortex.read more
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Journal ArticleDOI
The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation
TL;DR: Celsus described four of the five cardinal signs of inflammation 2000 years ago, and Eustachio discovered the adrenal glands almost 500 years ago; but not until 1936 did Selye note that in rats exposed to stressors, the adrenAL glands were enlarged, and the thymus and lymph nodes shrunken.
Journal ArticleDOI
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
TL;DR: Findings are reviewed that have documented which cytokines have been shown to influence hormone secretion from the HPA axis, determined under what physiological/pathophysiological circumstances endogenous cytokines regulate HPAaxis activity, established the possible sites of cytokine action on HPA Axis hormone secretion, and identified the potential neuroanatomic and pharmacological mechanisms by which cytokine signal the neuroendocrine hypothalamus.
Book ChapterDOI
Interleukin-1 and its biologically related cytokines.
TL;DR: Interleukin-1 (IL-1) and tumor necrosis factor (TNF) participate in self-augmentation induction mechanisms in cultured cells stimulated with viruses, bacterial toxins, and active complement components, and of immune complex.
Journal ArticleDOI
The syntax of immune-neuroendocrine communication
TL;DR: Edwin Blalock discusses how these shared ligands and receptors are used as a common chemical language for communication within and between the immune and neuroendocrine systems, suggesting an immunoregulatory role for the brain and a sensory function for the immune system.
Journal ArticleDOI
The immune-hypothalamic-pituitary-adrenal axis.
TL;DR: This review intends to examine the interactions between the immune system and the hypothalamic-pituitary-adrenal (HPA) axis and discusses products and components from theimmune system that stimulate or inhibit the HPA axis.