Journal ArticleDOI
Early repolarization syndrome: clinical characteristics and possible cellular and ionic mechanisms.
Ihor Gussak,Charles Antzelevitch +1 more
TLDR
The clinical characteristics and cellular and ionic basis for early repolarization syndrome and the characteristics of ERS need to be more fully delineated within the framework of what has been learned about the Brugada syndrome in recent years are addressed.About:
This article is published in Journal of Electrocardiology.The article was published on 2000-10-01. It has received 333 citations till now. The article focuses on the topics: Brugada syndrome & Benign early repolarization.read more
Citations
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Journal ArticleDOI
Sudden Cardiac Arrest Associated with Early Repolarization
Michel Haïssaguerre,Nicolas Derval,Frederic Sacher,Laurence Jesel,Isabel Deisenhofer,Luc De Roy,Jean-Luc Pasquié,Akihiko Nogami,Dominique Babuty,Sinikka Yli-Mäyry,Christian de Chillou,Patrice Scanu,Philippe Mabo,Seiichiro Matsuo,Vincent Probst,Solena Le Scouarnec,Pascal Defaye,Juerg Schlaepfer,Thomas Rostock,Dominique Lacroix,Dominique Lamaison,Thomas Lavergne,Yoshifusa Aizawa,Anders Englund,Frédéric Anselme,Mark D O'Neill,Mélèze Hocini,Kang-Teng Lim,Sébastien Knecht,George D. Veenhuyzen,Pierre Bordachar,Michel Chauvin,Pierre Jaïs,Gaelle Coureau,Geneviève Chêne,George Klein,Jacques Clémenty +36 more
TL;DR: Among patients with a history of idiopathic ventricular fibrillation, there is an increased prevalence of early repolarization and during a mean (+/-SD) follow-up of 61+/-50 months, defibrillator monitoring showed a higher incidence of recurrent ventricularfibrillation in case subjects with a repolarized abnormality than in those without such an abnormality.
Journal ArticleDOI
Long-Term Outcome Associated with Early Repolarization on Electrocardiography
Jani T. Tikkanen,Olli Anttonen,Juhani Junttila,Aapo L. Aro,Tuomas Kerola,Harri Rissanen,Antti Reunanen,Heikki V. Huikuri +7 more
TL;DR: An early-repolarization pattern in the inferior leads of a standard electrocardiogram is associated with an increased risk of death from cardiac causes in middle-aged subjects.
Journal ArticleDOI
Recommendations for interpretation of 12-lead electrocardiogram in the athlete
Domenico Corrado,Antonio Pelliccia,Hein Heidbuchel,Sanjay Sharma,Mark S. Link,Cristina Basso,Alessandro Biffi,Gianfranco Buja,Pietro Delise,Ihor Gussac,Aris Anastasakis,Mats Börjesson,Hans Bjornstad,François Carré,Asterios Deligiannis,Dorian Dugmore,Robert Fagard,Jan Hoogsteen,Klaus Peter Mellwig,Nicole Panhuyzen-Goedkoop,Erik Ekker Solberg,Luc Vanhees,Jonathan A. Drezner,N.A. Mark Estes,Sabino Iliceto,Barry J. Maron,Roberto Peidro,Peter J. Schwartz,Ricardo Stein,Gaetano Thiene,Paolo Zeppilli,William J. McKenna +31 more
TL;DR: The present position paper provides cardiologists and sports medical physicians with a modern approach to correct interpretation of 12-lead ECG in the athlete and emerging understanding of incomplete penetrance of inherited cardiovascular disease.
Journal ArticleDOI
Voltage-gated potassium channels as therapeutic targets
TL;DR: The human genome encodes 40 voltage-gated K+ channels, which are involved in diverse physiological processes ranging from repolarization of neuronal and cardiac action potentials, to regulating Ca2+ signalling and cell volume, to driving cellular proliferation and migration.
Journal ArticleDOI
J-Point Elevation in Survivors of Primary Ventricular Fibrillation and Matched Control Subjects: Incidence and Clinical Significance
Raphael Rosso,Evgeni Kogan,Bernard Belhassen,Uri Rozovski,Melvin M. Scheinman,David Zeltser,Amir Halkin,Arie Steinvil,Karin Heller,Michael Glikson,Amos Katz,Sami Viskin +11 more
TL;DR: J-point elevation is found more frequently among patients with idiopathic VF than among healthy control subjects and the frequency of J- point elevation among young athletes is intermediate.
References
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Book
Cardiac Electrophysiology : From Cell to Bedside
Douglas P. Zipes,José Jalife +1 more
TL;DR: Part I - Molecular Bases Of Ion Channel Activity PART II - Biophysics and Regulation of Cardiac Ion Channels PART III - Pharmacology of Card cardiac Ion Ch channels PART IV - Cellular Electrophysiology PART V - Models of Cardiopulmonary Excitation PART VI - Neural Control ofCardiac Electrical Activity
Journal ArticleDOI
Cellular Basis for the Brugada Syndrome and Other Mechanisms of Arrhythmogenesis Associated With ST-Segment Elevation
Gan-Xin Yan,Charles Antzelevitch +1 more
TL;DR: Depression or loss of the action potential dome in RV epicardium creates a transmural voltage gradient that may be responsible for the ST-segment elevation observed in the Brugada syndrome and other syndromes exhibiting similar ECG manifestations.
Book
Textbook of Cardiovascular Medicine
TL;DR: This volume covers aspects of cardiology from molecular genetics, to preventive cardiology, to state-of-the-art interventional cardiology techniques, to healthcare policy trends that affect cardiovascular medicine.
Journal ArticleDOI
Cellular Basis for the Electrocardiographic J Wave
Gan-Xin Yan,Charles Antzelevitch +1 more
TL;DR: The results provide the first direct evidence in support of the hypothesis that heterogeneous distribution of a transient outward current-mediated spike-and-dome morphology of the action potential across the ventricular wall underlies the manifestation of the electrocardiographic J wave.
Journal ArticleDOI
Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells.
Charles Antzelevitch,Serge Sicouri,Silvio H. Litovsky,Anton Lukas,S C Krishnan,J. M. Di Diego,G. A. Gintant,Da-Wei Liu +7 more
TL;DR: In spite of important advances in cardiology in recent years, pharmacological control of cardiac arrhythmias in the clinic remains an experiment conducted on a patient-by-patient basis using a trial and error approach tempered by good clinical judgment.
Related Papers (5)
Sudden Cardiac Arrest Associated with Early Repolarization
Michel Haïssaguerre,Nicolas Derval,Frederic Sacher,Laurence Jesel,Isabel Deisenhofer,Luc De Roy,Jean-Luc Pasquié,Akihiko Nogami,Dominique Babuty,Sinikka Yli-Mäyry,Christian de Chillou,Patrice Scanu,Philippe Mabo,Seiichiro Matsuo,Vincent Probst,Solena Le Scouarnec,Pascal Defaye,Juerg Schlaepfer,Thomas Rostock,Dominique Lacroix,Dominique Lamaison,Thomas Lavergne,Yoshifusa Aizawa,Anders Englund,Frédéric Anselme,Mark D O'Neill,Mélèze Hocini,Kang-Teng Lim,Sébastien Knecht,George D. Veenhuyzen,Pierre Bordachar,Michel Chauvin,Pierre Jaïs,Gaelle Coureau,Geneviève Chêne,George Klein,Jacques Clémenty +36 more