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Open AccessJournal ArticleDOI

Ebola virus disease and its complications

TLDR
By publishing peer review reports with published papers, the most transparent and toughest ‘Advanced OPEN peer review’ system will be helpful to many authors for drafting their article according to the specifications and will help to eradicate any possible malicious/purposeful interference by any person during peer review.
Abstract
In African countries Ebola virus has been responsible for several deaths. In addition to being a global health concern, the virus is also considered a potential biological threat.  Ebola viruses are incompletely understood pathogens that cause severe, often fatal, illnesses in humans and non-human primates. Ebola virus disease affects most of the human being and finally mortality rate increases in that county. Most of the countries are on alert for the ebola virus because peoples have worked within the boundaries of the affected area of Africa. Such people are not permitted to enter in the resident country without proper test at airport or other places.  In this review we have discussed ebola virus disease and  it affects the peoples worldwide. Peer Review History: Article received on- 3 August;    Revised on- 10 September; Accepted on- 15 October , Available online 15 November 2016 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:  Reviewer's Comments: Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Dr. Viney Chawla, University Institute of Pharmaceutical Sciences, Baba Farid University of Health Sciences, Sadiq Road, Faridkot-Punjab 151203, drvineychawla@gmail.com Dr. Tamer Elhabibi, Suez Canal University, Egypt, tamer_hassan@pharm.suez.edu.eg

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References
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Book

Virus taxonomy: classification and nomenclature of viruses. Seventh report of the International Committee on Taxonomy of Viruses.

TL;DR: This report builds on the accumulated taxonomic construction of the eight previous reports dating back to 1971 and records the proceedings of the Committee since publication of the last report in 2005.
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Basic Clinical and Laboratory Features of Filoviral Hemorrhagic Fever

TL;DR: This compilation will be of value to medical workers responding to epidemics and to investigators attempting to develop animal models of filoviral HF by identifying key unanswered questions and gaps in clinical data that will help guide clinical research in future outbreaks.
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Ebola 2014 — New Challenges, New Global Response and Responsibility

TL;DR: Three core interventions have stopped every previous outbreak and can stop this one: exhaustive case and contact finding, effective response to patients and the community, and preventive interventions.
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Advanced antisense therapies for postexposure protection against lethal filovirus infections

TL;DR: Administration of positively charged phosphorodiamidate morpholino oligomers (PMOplus), delivered by various dosing strategies initiated 30–60 min after infection, protects >60% of rhesus monkeys against lethal Zaire Ebola virus (ZEBOV) and 100% of cynomolgus monkeysagainst Lake Victoria Marburg virus (MARV) infection.