Effect of Bactericidal Substance from Staphylococcus aureus on Group A Streptococci I. Biochemical Alterations
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TLDR
A bactericidal substance isolated from phage type 71 staphylococci has been studied relative to its mechanism of action on streptococcal cells as discussed by the authors, which results in immediate cessation of protein and deoxyribonucleic acid synthesis.Abstract:
A bactericidal substance isolated from phage type 71 staphylococci has been studied relative to its mechanism of action on streptococcal cells. The substance exerts its effect best at 37 C. No cell lysis occurs as evidenced by lack of alteration in optical density of susceptible cell suspensions. The bactericidal substance results in immediate cessation of protein and deoxyribonucleic acid synthesis as well as degradation of newly and previously formed ribonucleic acid (RNA). The action on RNA seems to be independent of protein synthesis.read more
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References
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Electron microscopic studies on streptococci i. m antigen
TL;DR: Ferritin-conjugated, type-specific antibodies localize on homologous M+ cells in a pattern suggestive of several M antigenic sites along the length of individual surface fimbria, suggesting the following hypothesis: M antigen is secreted by the cell, is partially excreted through the otherwise intact cell wall, and is bound by the wall so that M protein occupies a peripheral, exposed position on the surfaces of the streptococcal cell wall.
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The Fine Structure Of Chondrococcus Columnaris: I. Structure and Formation of Mesosomes
TL;DR: Cells of Chondrococcus columnaris were sectioned and examined in the electron microscope after fixation by two different methods, and the mesosomes appeared as highly organized structures produced by the invagination and proliferation of the plasma membrane.
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Demonstration of a Bactericidal Substance Against β-Hemolytic Streptococci in Supernatant Fluids of Staphylococcal Cultures
TL;DR: Staphylococcal skin isolates belonging to phage type 71 were found to produce a bactericidal substance that was nondialyzable and could be precipitated with ammonium sulfate, and a quantitative variation observed to exist among susceptible organisms was a function of the inoculum size of the inhibited strains.