Journal ArticleDOI
Effect of discrete kainic acid-induced lesions of corpus caudatus and globus pallidus on glutamic acid decarboxylase of rat substantia nigra.
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TLDR
Results indicate that nigral GAD arises mostly from the body and, in part, also from the head of the caudate but not from the globus pallidus or from the tail of the Caudate, where it is likely that it is derived from nigral GABAergic terminals.About:
This article is published in Brain Research.The article was published on 1980-05-05. It has received 58 citations till now. The article focuses on the topics: Globus pallidus & Substantia nigra.read more
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Circuitry of Primate Prefrontal Cortex and Regulation of Behavior by Representational Memory
TL;DR: The sections in this article are: Essence of Prefrontal Function: Regulation of Behavior by Representational Knowledge, Multiple Subsystems of Pre Frontal Cortex: Unity or Diversity of Function, and Functional Speculations.
Journal ArticleDOI
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization
TL;DR: Immunocytochemical studies indicate that DARPP-32, is present in the subclass of dopaminoceptive neurons containing D-1 receptors (dopamine receptors coupled to adenylate cyclase) and may be an effective marker for certain of the actions of dopamine that are mediated through cAMP and its associated protein kinase.
Journal ArticleDOI
Modification of saccadic eye movements by GABA-related substances. II. Effects of muscimol in monkey substantia nigra pars reticulata.
Okihide Hikosaka,Robert H. Wurtz +1 more
TL;DR: It is concluded that a substantial fraction of GABA-mediated inhibitory inputs in the SC originates from the substantia nigra pars reticulata, which exerts a tonic inhibition on saccade-related cells in SC and that this inhibition is mediated by GABA.
Journal ArticleDOI
The basal ganglia and the locomotor regions.
TL;DR: From various lines of evidence, it appears that the PPN/MLR receives elements of information from the motor cortex and basal ganglia centers involved in postural control, and may be involved in the relay of information useful in the control of the center of gravity and other postural functions during locomotion.
Journal ArticleDOI
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain
SI Walaas,P Greengard +1 more
TL;DR: The present study documents the existence in mammalian brain of a phosphoprotein which may play a biological role in dopaminoceptive neurons, which has been designated DARPP-32 (dopamine- and adenosine 3′:5′-monophosphate-regulated phosphop Protein-32,000).
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In situ injection of kainic acid: A new method for selectively lesioning neuronal cell bodies while sparing axons of passage
TL;DR: These morphologic studies provide (direct) evidence that in situ injection of kainic acid in brain causes a selective degeneration of neurons with cell bodies in the area of the injection but spares axons that arise from perikarya outside the region but pass through or terminate in the injected area.