Showing papers in "Brain Research in 1980"
••
TL;DR: The efferent connections of the parabrachial nucleus have been analyzed in the rat using the anterograde autoradiographic method and two major differences have been noted.
1,161 citations
••
TL;DR: This finding suggests that GABA-mediated inhibition of GABA neurons may occur in the NR of normal (untreated) rats, and the large number of GAD-positive cell bodies within the NR contrasts with a paucity of positively-stained somata in the more internally located thalamic nuclei.
661 citations
••
TL;DR: During normal walking this mechanism could be of major importance during stance to prevent the initiation of the swing phase of a time when hindlimb extension is fully needed to support the weight of the animal.
580 citations
••
TL;DR: The findings indicate that certain agranular or dysgranular cortical regions may project directly to the amygdala: in particular, the orbital frontal cortex, anterior cingulate gyrus, subcallosal gyrus), temporal pole and anterior insula.
579 citations
••
TL;DR: Repeated administration of high doses of methamphetamine produced long-term decreases in dopamine levels and in the number of DA uptake sites in the rat striatum, which were dose-related and did not appear to be due to the continued presence of drug in striatal tissue.
539 citations
••
TL;DR: It is concluded that SN transplants reinnervation the dorsal part of the neostriatum are able to replace the innate SN in normalizing some aspects of the rats motor behaviour, while their sensorimotor deficits and deficits in consummatory behaviour were unaffected.
536 citations
••
TL;DR: Various doses of 6-hydroxydopamine injected into the rat substantia nigra produced partial, dose-dependent lesions of the dopaminergic nigrostriatal tract that accelerated dopamine's synthesis in, and release from, surviving neurons, as indicated by increased striatal levels of the dopamine metabolites dihydroxyphenylacetic acid and homovanillic acid.
515 citations
••
TL;DR: The regional pattern of reduced 5-HT levels following methylamphetamine is similar to that seen after p-chloroamphetamine, and Serotonergic systems are more sensitive than DA systems to the apparent neurotoxic actions of methylamphetamine.
496 citations
••
TL;DR: It is concluded that spread of seizure activity from the injection site plays a crucial role in the induction of "remote" brain damage after focal intracerebral injections.
403 citations
••
TL;DR: The luminal and antiluminal membranes of brain capillaries are biochemically and functionally different and this polarity should permit active solute transport across brain capillary endothelial cells which are the cells responsible for the blood-brain barrier.
390 citations
••
TL;DR: Fiber density was moderate in the tuberculum olfactoriu, anterior hypothalamus including the medial preoptic area, mediobasal hypothalamus, periventricular thalamus, lateral lemniscal system, parabrachial nucleus, nucleus solitarius, and area postrema.
••
TL;DR: Results show a preferential ordering in the reinnervation of dentate granule cells which is not readily explained by proximity to the degenerating fibers and also that removal of CA3-CA4-derived innervation more readily elicits translaminar growth in the fascia dentata than in area CA1.
••
TL;DR: It is concluded that the appearance and asymmetry of event-preceding negative potentials reflect preparation to execute specific motor acts.
••
TL;DR: The results suggest that 5-HT and NA enhance the effects of excitatory inputs to spinal motoneurones by actions on separate receptors.
••
TL;DR: Two vocal control nuclei of the canary telencephalon, hyperstriatum ventrale, pars caudale (HVc) and nucleus robustus archistriatalis (RA), are larger in males, that learn complex songs, than in females, that normally do not sing.
••
TL;DR: Data indicate that there are two physiologically distinct subdivisions of the perforant path and that the interpathway differences are at least partly due to differential quantal contents of the EPSP under resting conditions.
••
TL;DR: Investigation of neurons in cerebellum and neocortex reveals that they are NNE(+) during migration and only become NSE(+) in their final location, presumably after making full synaptic connections.
••
TL;DR: Only rats with functional hippocampal systems were able to perform the maze task accurately while thos rats with lesions in the hippocampal system were not.
••
TL;DR: The present data provide further evidence for the modulatory role of a spinal noradrenergic system on the spinal processing of nociceptive transmission and no cross-tolerance between intrathecal NE and morphine was observed, suggesting that the spinal action of morphine is not mediated by spinal nordrenergic terminals.
••
TL;DR: The morphological features of striatal projection neurons and the responses of these neurons to electrical stimulation of the substantia nigra were studied in rats through the methods of intracellular recording and intrACEllular labeling with the enzyme horseradish peroxidase.
••
TL;DR: In both adult and young subjects there was a significant correlation between blood pressure and pain sensitivity: hypertensives had a higher threshold for sensation of pain in the tooth-pulp test than normotensive controls.
••
TL;DR: Observations are interpreted according to the hypothesis that penicillin and bicuculline block cellular IPSPs, and consequently allow remote intrinsic excitatory events to invade the cell soma and trigger action potentials.
••
TL;DR: A regular slow wave theta rhythm can be recorded in the medial entorhinal cortex (MEC) of freely moving rats during voluntary behaviors and paradoxical sleep.
••
TL;DR: An attempt is made to explain how the complex and variable efferent activity can arise from an initially simple rhythmic command and produce the biomechanically adapted locomotor movement of the hindlimb.
••
TL;DR: Findings lead to the hypothesis that folliculostellate cells may belong to the neuroectodermal cells and may be specialized cells playing some unknown role in rat adenohypophysis.
••
TL;DR: The results are discussed in relation to the current concepts of the involvement of substance P and opiate systems in nociception and the potential use of neonatal capsaicin as a selective neurotoxin for the elucidation of the spinal mechanisms of pain.
••
TL;DR: The present results confirm that there is a substantial drop in the substance P content of the globus pallidus and substantia nigra, and there was also a reduction in the Met-enkephalin content of these areas, and this result suggests the loss of striato-pallidal and Striato-nigral substance P and enkphalin-containing projections in Huntington's disease.
••
TL;DR: The spatial distribution of neurons with different binaural response properties has been studied within the three dimensions of the primary auditory cortex (AI) in the cat and the implications for the concept of AI as a unitary element in auditory processing are discussed.
••
TL;DR: It is suggested that kainic acid destroys neurons indirectly, by initiating a prolonged status epilepticus that is lethal to seizure-sensitive neurons, such as the hippocampal pyramidal cells.
••
TL;DR: The widespread distribution of SRIF is consistent with radioimmunoassay data and suggests a diverse physiological role for somatostatin, and widespread accumulations of fibers were observed throughout the telencephalon.