Effect of neonatal circumcision on pain response during subsequent routine vaccination
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Circum circumcised infants showed a stronger pain response to subsequent routine vaccination than uncircumcised infants, and preoperative treatment with Emla attenuated the painresponse to vaccination.About:
This article is published in The Lancet.The article was published on 1997-03-01 and is currently open access. It has received 1099 citations till now. The article focuses on the topics: Visual analogue scale.read more
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Sociosexuality from Argentina to Zimbabwe: a 48-nation study of sex, culture, and strategies of human mating.
TL;DR: Sex differences in sociosexuality were generally large and demonstrated cross-cultural universality across the 48 nations of the ISDP, confirming several evolutionary theories of human mating.
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Can adverse neonatal experiences alter brain development and subsequent behavior
TL;DR: It is proposed that lack of N-methyl-D-aspartate (NMDA) receptor activity from maternal separation and sensory isolation leads to increased apoptosis in multiple areas of the immature brain, promoting two distinct behavioral phenotypes characterized by increased anxiety, altered pain sensitivity, stress disorders, hyperactivity/attention deficit disorder, and impaired social skills and patterns of self-destructive behavior.
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Facial expression of pain: an evolutionary account.
TL;DR: It is proposed that human expression of pain in the presence or absence of caregivers, and the detection of pain by observers, arises from evolved propensities.
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Long-term consequences of pain in human neonates.
TL;DR: There are multiple sources of stress in the NICU, which contribute to inducing high overall 'allostatic load', therefore determining specific effects of neonatal pain in human infants is challenging.
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Circumcision Policy Statement
TL;DR: Evaluation of current evidence indicates that the health benefits of newborn male circumcision outweigh the risks and that the procedure’s benefits justify access to this procedure for families who choose it.
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Practical statistics for medical research
TL;DR: Practical Statistics for Medical Research is a problem-based text for medical researchers, medical students, and others in the medical arena who need to use statistics but have no specialized mathematics background.
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Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence
TL;DR: This review examines the clinical and experimental evidence which points to a contribution of central Neurol plasticity to the development of pathological pain, and assesses the physiological, biochemical, cellular and molecular mechanisms that underlie plasticity induced in the central nervous system in response to noxious peripheral stimulation.
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The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states.
TL;DR: Results indicate that NMDA receptors are involved in the induction and maintenance of the central sensitization produced by high threshold primary afferent inputs and have a bearing both on the potential role of NMDA antagonists for pre‐emptive analgesia and for treating established pain states.