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Journal ArticleDOI

Effects of body position on regional pulmonary blood flow during acute pulmonary edema in dogs: A positron emission tomography study

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TLDR
The benefits of the prone position on oxygenation are related to both the spatial distribution of lung water accumulation and regional pulmonary blood flow.
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This article is published in Journal of Critical Care.The article was published on 1991-03-01. It has received 13 citations till now. The article focuses on the topics: Prone position & Lung injury.

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Citations
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Journal ArticleDOI

Prone positioning attenuates and redistributes ventilator-induced lung injury in dogs.

TL;DR: In this model of lung injury induced solely by mechanical forces, the prone position resulted in a less severe and more homogeneous distribution of ventilator‐induced lung injury, which parallel those previously obtained in oleic acid‐preinjured animals ventilated with higher positive end‐expiratory pressure.
Journal ArticleDOI

Effect of prone position on regional shunt, aeration, and perfusion in experimental acute lung injury.

TL;DR: In a surfactant-deficient model of lung injury, the prone position improved gas exchange by restoring aeration and decreasing shunt while preserving perfusion in dorsal lung regions, and by making the distribution of ventilation more uniform.
Journal ArticleDOI

Oxygenation Response to a Recruitment Maneuver during Supine and Prone Positions in an Oleic Acid–Induced Lung Injury Model

TL;DR: The results suggest that a RM improves oxygenation more effectively with a decreased PEEP requirement for the preservation of the oxygenation response in prone compared with supine position.
Journal ArticleDOI

Role of cyclooxygenase-2 in oleic acid-induced acute lung injury.

TL;DR: The effect of endotoxin on pulmonary perfusion in ALI is therefore the result of a COX-2-mediated increase in prostacyclin production in lung tissue.
References
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Journal ArticleDOI

Improved oxygenation in patients with acute respiratory failure: the prone position.

TL;DR: Six patients with acute respiratory failure were turned from supine to prone, supporting the upper thorax and pelvis and allowing the abdomen to protrude, and arterial PO2 increased, permitting a decrease in inspired oxygen concentration or positive end-expiratory pressure when prone.
Journal ArticleDOI

The prone position in ARDS patients. A clinical study.

TL;DR: In this article, the gas exchange and hemodynamics were evaluated before, during, and after a two-hour period of prone position in 13 moderate-severe ARDS patients in both supine and prone positions.
Journal ArticleDOI

Fractal properties of pulmonary blood flow: characterization of spatial heterogeneity.

TL;DR: The heterogeneity of pulmonary blood flow was examined using a fractal analytic procedure, and the results were compared with the traditional gravitational model of flow distribution, suggesting that gravitation plays a secondary role to an underlying process producing heterogeneity.
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