Journal ArticleDOI
Effects of estrogen deficiency on tooth movement after force application: an experimental study in ovariectomized rats.
TLDR
Estrogen deficiency increased orthodontic tooth movements but counts of osteoblasts, which are responsible for new bone formation, were lower in regions of tension and of pressure.Abstract:
Objective. The aim of this study was to investigate the effects of estrogen deficiency on tooth movement in ovariectomized rats. Material and methods. Forty-two adult female Sprague-Dawley rats were assigned at random to one of the following groups: test group (n=20), ovariectomized rats (or estrogen-deficient rats); control group (n=22), non-ovariectomized rats. Two months after ovariectomy, expansion springs exerting 10 g of force were inserted between the upper central incisors in both groups. The amount of movement was measured daily until tooth movement began and then at intervals of 3 days. The rats were sacrificed 18 days after applying the expansion spring and histomorphometric analysis was performed along the left upper central incisor root towards the apex of the alveolar bone. Results. The amount and speed of movement was observed to be greater in ovariectomized rats. On histomorphometric analysis, osteoblast and osteocyte counts on the pressure side were higher in the non-ovariectomized group ...read more
Citations
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Journal ArticleDOI
Estrogen deficiency increases variability of tissue mineral density of alveolar bone surrounding teeth.
TL;DR: Higher variability of mineralization observed in AB of OVX group indicates that estrogen deficiency amplifies the active bone remodeling of AB already present due to the mastication, suggesting that the increased variability of TMD induced by estrogen deficiency may compromise the mechanical stability of the tooth-bearing alveolar bone.
Journal ArticleDOI
Effect of ovarian activity on orthodontic tooth movement and gingival crevicular fluid levels of interleukin-1β and prostaglandin E2 in cats
TL;DR: It is indicated that ovarian activity can affect orthodontic tooth movement and GCF levels of IL-1β and PGE(2) in cats.
Journal ArticleDOI
Corticotomy affects both the modus and magnitude of orthodontic tooth movement
TL;DR: This study suggests that the moment-to-force ratios used in conventional orthodontics should be modified in case of techniques that decrease bone density to enhance tooth movement rate.
Journal ArticleDOI
Osteoprotective Effects of Estrogen in the Maxillary Bone Depend on ERα
Soraia Macari,L. Ajay Sharma,Amanda Wyatt,Penelope J. Knowles,Raphael E. Szawka,Gustavo Pompermaier Garlet,David R. Grattan,George J. Dias,Tarcília Aparecida Silva +8 more
TL;DR: Estrogen deficiency results in disruption of maxillary alveolar bone microarchitecture, which is linked to bone cell differentiation and apoptosis, as well as local production of inflammatory molecules such as IL-33, TNF-α, and IL-1β.
Journal ArticleDOI
Force-induced increased osteogenesis enables accelerated orthodontic tooth movement in ovariectomized rats
Qinggang Dai,Siru Zhou,Peng Zhang,Xuhui Ma,Nayong Ha,Xiao Yang,Zhifeng Yu,Bing Fang,Lingyong Jiang +8 more
TL;DR: It is suggested that increased osteogenesis may compensate for the increased bone resorption during and after OTM and enable effective accelerated OTM in OVX rats.
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