Journal ArticleDOI
Effects of sub-lethal levels of dichlorodiphenyltrichloroethane and dichlorodiphenyldichloroethylene on in vitro steroid biosynthesis by ovarian follicles or steroid metabolism by embryos of rainbow trout (Oncorhynchus mykiss).
TLDR
It is suggested that although DDT and DDE may affect ovarian androgen synthesis under some conditions, under the conditions of the present study, they do not impact on overall rates of gonadal estrogen synthesis.About:
This article is published in Aquatic Toxicology.The article was published on 2005-07-01. It has received 1 citations till now. The article focuses on the topics: Steroid biosynthesis & Dichlorodiphenyldichloroethylene.read more
Citations
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Journal ArticleDOI
Cortisol Inhibition of 17b-Estradiol Secretion by Rainbow Trout Ovarian Follicles Involves Modulation of Star and P450scc Gene Expression
TL;DR: The study shows that maternal stress during the critical phase of follicle vitellogenesis will have deleterious effects on oocyte development and growth, and cortisol inhibition of steroidogenesis is prior to the synthesis of progestogens.
References
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Journal ArticleDOI
Endocrine sex control strategies for the feminization of teleost fish
TL;DR: This review concentrates on the use of oestrogens for sex control, discussing the advantages of producing monosex female stocks for finfish aquaculture, and pointing out those cases in which hormonal sex reversal technology is worth applying.
Journal ArticleDOI
DDT-induced feminization of gull embryos
TL;DR: Developmental feminization of males is associated with inability to breed as adults and may explain the highly skewed sex ratio and reduced number of male gulls breeding on Santa Barbara Island in southern California.
Journal ArticleDOI
Xenoestrogens at Picomolar to Nanomolar Concentrations Trigger Membrane Estrogen Receptor-α–Mediated Ca2+ Fluxes and Prolactin Release in GH3/B6 Pituitary Tumor Cells
TL;DR: Investigation of the effects of E2 versus several XEs on the pituitary tumor cell subline GH3/B6/F10 indicates that at very low concentrations, XEs mediate membrane-initiated intracellular Ca2+ increases resulting in PRL secretion via a mechanism similar to that for E2, but with distinct patterns and potencies that could explain their abilities to disrupt endocrine functions.
Journal ArticleDOI
Vinclozolin and p,p'-DDE alter androgen-dependent gene expression : in vivo confirmation of an androgen receptor-mediated mechanism
TL;DR: Data indicate that vinclozolin and p,p'-DDE act as antiandrogenic developmental effects in vivo by altering the expression of androgen-dependent genes.
Journal ArticleDOI
Interaction of environmental chemicals with the estrogen and progesterone receptors from the oviduct of the American alligator.
TL;DR: Results provide the first evidence that environmental chemicals bind the aER and aPR from the American alligator, supporting the hypothesis that the reported reproductive abnormalities may be related to the modulation of endocrine-related responses.
Related Papers (5)
Estrogenic activity of chlordecone, o,p′-DDT and o,p′-DDE in juvenile rainbow trout: induction of vitellogenesis and interaction with hepatic estrogen binding sites
DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor beta.
The diverse mechanism of action of dichlorodiphenyldichloroethylene (DDE) and methoxychlor in ovarian cells in vitro
P. Jorge Chedrese,Falter Feyles +1 more