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Journal ArticleDOI

Enhanced reproductive toxicities induced by phthalates contaminated microplastics in male mice (Mus musculus).

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TLDR
Compared with virgin MPs and PAEs alone, PAE-contaminated MPs induced enhanced reproductive toxicities manifested by greater alterations in sperm physiology and spermatogenesis, which provide valuable insights into the mechanism of combined toxicity of MPs and other pollutants.
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This article is published in Journal of Hazardous Materials.The article was published on 2021-03-15. It has received 68 citations till now. The article focuses on the topics: Reproductive toxicity.

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Microplastic-contaminated antibiotics as an emerging threat to mammalian liver: enhanced oxidative and inflammatory damages.

TL;DR: In this paper , a mouse model for human physiology was employed to find that concurrent exposure to the major types of antibiotics and microplastics would result in evident accumulation in detoxification organs; specifically, liver could amass 41.70 μg kg-1 of sulfamethoxazole (SMZ) while 3.83% of microplastic was accumulated in the kidney.
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A preliminary study about the potential risks of the UV-weathered microplastic: The proteome-level changes in the brain in response to polystyrene derived weathered microplastics.

TL;DR: In this paper , the chemical changes of WMPs generated under laboratory-synchronized environmentally mimetic conditions and compared them with virgin MPs (VMPs) were found to have a rough surface, slight yellow color, reduced molecular weight, and structural alteration compared with those of VMP.
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Reproductive toxicity of micro- and nanoplastics.

TL;DR: In this article , the authors summarized the effects of micro/nanoplastics on the reproduction of different organisms including terrestrial and marine invertebrates and vertebrates, the amplification of toxic effects between them through the food chain, the serious threat to biodiversity, and the imminent challenge to human reproductive health.
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Polystyrene nanoplastics exacerbated Pb-induced liver toxicity in mice.

TL;DR: In this article, the adverse effect of nanoplastics and heavy metals on liver, single or in combination, was evaluated in a study, and the results showed that the Pb content in co-exposure group of nanoparticles and Pb (PN group) was higher than the group exposed to Pb alone (Pb group).
References
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Journal ArticleDOI

The physical impacts of microplastics on marine organisms: a review.

TL;DR: This review focuses on marine invertebrates and their susceptibility to the physical impacts of microplastic uptake and an assessment of the relative susceptibility of different feeding guilds.
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Plastic and Human Health: A Micro Issue?

TL;DR: There is potential for microplastics to impact human health, and assessing current exposure levels and burdens is key to guide future research into the potential mechanisms of toxicity and hence therein possible health effects.
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Oyster reproduction is affected by exposure to polystyrene microplastics

TL;DR: Evidence is provided that micro-PS cause feeding modifications and reproductive disruption in oysters, with significant impacts on offspring, providing ground-breaking data on microplastic impacts in an invertebrate model, helping to predict ecological impact in marine ecosystems.
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Microplastics in freshwaters and drinking water: Critical review and assessment of data quality.

TL;DR: More high quality data is needed on the occurrence of microplastics in drinking water, to better understand potential exposure and to inform human health risk assessments, and there is a significant need to improve quality assurance ofmicroplastic sampling and analysis in water samples.
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Microplastics as an emerging threat to terrestrial ecosystems

TL;DR: The pervasive microplastic contamination as a potential agent of global change in terrestrial systems is introduced, the physical and chemical nature of the respective observed effects are highlighted, and the broad toxicity of nanoplastics derived from plastic breakdown is discussed.
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