Journal ArticleDOI
Environmentally benign synthesis of heterocyclic compounds by combined microwave-assisted heterogeneous catalytic approaches†
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In this article, the application of heterogeneous catalysis combined with microwave irradiation in the synthesis of heterocyclic compounds is reviewed and the authors highlight the environmentally benign and sustainable nature of the combined microwave-assisted heterogeneous catalytic methods, highlighting the green aspects of individual synthetic approaches.About:
This article is published in Green Chemistry.The article was published on 2012-01-01. It has received 205 citations till now.read more
Citations
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Journal ArticleDOI
Application of microwave-assisted heterogeneous catalysis in sustainable synthesis design
TL;DR: An overview of recent advances in microwave assisted heterogeneous catalysis is provided in this article, mainly focusing on the past 5-6 years, in microwave-assisted heterogeneous Catalysis.
Journal ArticleDOI
A facile protocol for the synthesis of 3-aminoimidazo-fused heterocycles via the Groebke–Blackburn–Bienayme reaction under catalyst-free and solvent-free conditions
TL;DR: In this paper, a one-pot catalyst, solvent, work-up and column free synthesis of 3-aminoimidazo-fused heterocycles by a three-component reaction of a 2aminoheterocycle, aldehyde, and isocyanide is presented.
Journal ArticleDOI
A simple and efficient synthesis of 3,4-dihydropyrimidin-2-(1H)-ones via Biginelli reaction catalyzed by nanomagnetic-supported sulfonic acid
TL;DR: In this paper, Nanomagnetic-supported sulfonic acid is found to be a new, powerful, and reusable heterogeneous catalyst for the rapid synthesis of 3,4-dihydropyrimidin-2-(1H)-ones under conventional heating and microwave irradiation.
Journal ArticleDOI
Catalytic procedures for multicomponent synthesis of imidazoles: selectivity control during the competitive formation of tri- and tetrasubstituted imidazoles
TL;DR: In this article, the performance of different fluoroboric acid-derived catalyst systems viz. aq HBF4, solid supported HBF 4, metal tetrafluoroborates (inorganic salts), solid supported metal tetra substituted imidazole, and tetra fluoroborate based ionic liquids (organic salts) were investigated for the three component reaction (3-MCR) of 1,2-diketone, aldehyde, and ammonium salts to form 2,4,5-trisubstituted imidsoles
Journal ArticleDOI
Microwave-assisted synthesis of nitrogen-containing heterocycles
TL;DR: In this paper, the microwave (MW) radiation is widely used as a source of heating in organic synthesis and it has emerged as a new green-method for organic synthesis as it provides spectacular acceleration, higher yields under milder reaction conditions, and higher product purities, and it reduces pollution of the environment through the use of solvent-free reaction protocols.
References
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Book
Green Chemistry: Theory and Practice
Paul T. Anastas,John C. Warner +1 more
TL;DR: Green Chemistry: What is green chemistry? as discussed by the authors presents the principles of green chemistry and evaluates the impact of chemistry on the environment. But, it is not a complete overview of all of the issues involved in green chemistry.
Book ChapterDOI
Receptors for Purines and Pyrimidines
Vera Ralevic,Geoffrey Burnstock +1 more
TL;DR: In this review particular emphasis is placed on the discrepancy between the concentrations ofadenosine, ADP, and ATP in the purine receptors of UDP and UTP.
Journal ArticleDOI
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells.
Brian J. Druker,Shu Tamura,Elisabeth Buchdunger,Sayuri Ohno,Gerald M. Segal,Shane Fanning,Jürg Zimmermann,Nicholas B. Lydon +7 more
TL;DR: A compound, designed to inhibit the Abl protein tyrosine kinase, was evaluated for its effects on cells containing the Bcr–Abl fusion protein and it was found that this compound may be useful in the treatment of bcr–abl–positive leukemias.
Journal ArticleDOI
Controlled microwave heating in modern organic synthesis.
TL;DR: This Review highlights recent applications of controlled microwave heating in modern organic synthesis, and discusses some of the underlying phenomena and issues involved.
Journal ArticleDOI
The growing impact of click chemistry on drug discovery.
TL;DR: The copper-(I)-catalyzed 1,2,3-triazole formation from azides and terminal acetylenes is a particularly powerful linking reaction, due to its high degree of dependability, complete specificity, and the bio-compatibility of the reactants.
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