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Evaluation of antibacterial, antioxidant and GC-MS analysis of ethanolic seed extract of Myristica dactyloides

TLDR
In this paper, the antimicrobial and antioxidant properties of ethanol extract of Myristica dactyloides were evaluated by the agar well diffusion method against E. coli, Klebsiella pneumonia, Streptococcus sp, and Staphylococcus aureus at different concentrations.
Abstract
In this present investigation we analysed the antimicrobial and antioxidant activities of ethanol extract of Myristica dactyloides. The antimicrobial activity of the ethanol extract was evaluated by the agar well diffusion method against of E. coli, Klebsiella pneumonia, Streptococcus sp, and Staphylococcus aureus at different concentrations. The antibacterial activity showed the result in a dose-dependent manner. The free radical scavenging was evaluated against DPPH, hydroxyl, and nitric oxide radicals. In DPPH, hydroxyl and nitric oxide scavenging assay showed the IC 50 value of the extract was found to be 20 μg/ml, 48.25 and 30 μg/ml, respectively. The plant can be considered as promising antioxidant properties with high potential value for drug development for various diseases.

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References
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Journal ArticleDOI

Extraction methods and bioautography for evaluation of medicinal plant antimicrobial activity

TL;DR: A comparative study on the antimicrobial properties of extracts from medicinal plants obtained by two different methods indicated that the diethyl ether extracts were the most efficient antimicrobial compounds.
Journal ArticleDOI

Antimicrobial resistance in developing countries.

C A Hart, +1 more
- 05 Sep 1998 - 
TL;DR: Better access to diagnostic laboratories is needed, as well as improved surveillance of the emergence of resistance, better regulation of antibiotics' use, and better education of the public, physicians, and veterinarians in the appropriate use of drugs.
Journal ArticleDOI

Antimicrobial resistance in developing countries. Part I: recent trends and current status

TL;DR: In this first part of the review, the present state of resistance in these infections is summarized from the available data and potential containment strategies that could address this burgeoning problem are reviewed.
Journal ArticleDOI

Free radicals in disease processes: a compilation of cause and consequence.

TL;DR: In this article, the authors present Free Radicals in Disease Processes: A Compilation of Cause and Consequence, Vol. 19, No. 3, pp. 141-158.
Journal ArticleDOI

The metabolic fate of dietary polyphenols in humans.

TL;DR: The results show that the majority of the in vivo forms derive from cleavage products of the action of colonic bacterial enzymes and subsequent metabolism in the liver, and suggest that consideration should be given to the cleavage Products as having a putative role as physiologically relevant bioactive components in vivo.
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