Evaluation of the safety of time-lapse observations for human embryos
Tatsuo Nakahara,Akira Iwase,Maki Goto,Toko Harata,Toko Harata,Miyabi Suzuki,Miki Ienaga,Harumi Kobayashi,Sachiko Takikawa,Shuichi Manabe,Fumitaka Kikkawa,Hisao Ando +11 more
Reads0
Chats0
TLDR
Time-lapse observations using an incubator with an integrated optical microscope may therefore be safely utilized in clinical practice, and no significant differences were observed in the fertilization rate or the rate of excellent-good cleavage embryos.Abstract:
Purpose
To assess the effects of light from an integrated optical microscope and evaluate the safety of time-lapse observations using a built-in microscope incubator.read more
Citations
More filters
Journal ArticleDOI
The use of morphokinetics as a predictor of embryo implantation
TL;DR: A multivariable model is proposed based on the findings to classify embryos according to their probability of implantation and it is proposed that the image acquisition and time-lapse analysis system makes it possible to determine exact timing of embryo cleavages in a clinical setting.
Journal ArticleDOI
Improving embryo selection using a computer-automated time-lapse image analysis test plus day 3 morphology: results from a prospective multicenter trial
Joe Conaghan,A.A. Chen,S.P. Willman,K. Ivani,Philip E. Chenette,Robert Boostanfar,Valerie L. Baker,G. David Adamson,Mary E. Abusief,M. Gvakharia,Kevin E. Loewke,Shehua Shen +11 more
TL;DR: Experienced embryologists using Eeva in combination with D3 morphology significantly improved their ability to identify embryos that would reach the usable blastocyst stage, and adjunctive use of morphology plus Eeva also reduced interindividual variability in embryo selection.
Journal ArticleDOI
Clinical validation of embryo culture and selection by morphokinetic analysis: a randomized, controlled trial of the EmbryoScope
TL;DR: The strategy of culturing and selecting embryos in the integrated EmbryoScope time-lapse monitoring system improves reproductive outcomes.
Journal ArticleDOI
Time-lapse monitoring as a tool for clinical embryo assessment
TL;DR: This mini-review summarizes the current knowledge about dynamic markers of viability and discusses the potential clinical role of time-lapse analysis in embryo assessment and selection.
Journal ArticleDOI
Embryo quality, blastocyst and ongoing pregnancy rates in oocyte donation patients whose embryos were monitored by time-lapse imaging.
Marı́a José Santa Cruz,Blanca Gadea,Nicolás Garrido,Kamilla Sofie Pedersen,Mar Martínez,Inma Pérez-Cano,Manuel Muñoz,Marcos Meseguer +7 more
TL;DR: It is concluded that time-lapse monitoring in the EmbryoScope does not impair embryo quality while allowing for morphological, spatial and temporal analysis of embryo development.
References
More filters
Journal ArticleDOI
The probability of abnormal preimplantation development can be predicted by a single static observation on pronuclear stage morphology
Jan Tesarik,Ermanno Greco +1 more
TL;DR: New evaluation criteria can be used to predict the developmental fate of human embryos as early as the pronuclear stage, without requiring repeated observations or an exact timing of pronuclear zygote inspection.
Journal ArticleDOI
Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography.
TL;DR: Time-lapse video cinematography is shown to be an excellent tool for studying fertilization and early embryo development, and it was found that good quality embryos arose from oocytes that had more uniform timing from injection to pronuclear abuttal and tended to have a longer cytoplasmic wave.
Journal ArticleDOI
The successful use of pronuclear embryo transfers the day following oocyte retrieval.
L.A. Scott,Samuel Smith +1 more
TL;DR: The data show that oocyte quality and pronuclear embryo morphology are related to implantation and that pronuclear embryos can be successfully selected for embryo transfer.
Journal ArticleDOI
Early embryo cleavage is a strong indicator of embryo quality in human IVF
TL;DR: Early embryo cleavage is a strong biological indicator of embryo potential, and may be used as an additional embryo selection factor for ICSI embryos.