Journal ArticleDOI
Even minimal symptoms of depression increase mortality risk after acute myocardial infarction
David E. Bush,Roy C. Ziegelstein,Matthew Tayback,Daniel Richter,Sandra S. Stevens,Howard Zahalsky,James A. Fauerbach +6 more
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Higher mortality was also observed at very low levels of depressive symptoms (BDI 4 to 9) not generally considered clinically significant and below the level usually considered predictive of increased post-AMI mortality.Abstract:
Mild to moderate levels of depressive symptoms as characterized by Beck Depression Inventory (BDI) scores of ≥10 are associated with decreased survival after acute myocardial infarction (AMI). We investigated whether lower levels of depressive symptoms are also associated with increased mortality risk after AMI. We prospectively studied 285 patients with AMI who survived to discharge for evidence, at the time of hospitalization, of a DSM-IIIR mood disorder (using a structured clinical interview) and for symptoms of depression (using the BDI). The overall mortality rate at 4 months was 6.7%. Multiple logistic regression (chi-square 35.79, p ≤0.001) revealed that the independent predictors of mortality were: age ≥65 years, left ventricular ejection fraction <35%, diabetes mellitus, and any depression (DSM-IIIR mood disorder or BDI ≥10) present at the time of AMI. Among patients ≥65 years old with left ventricular ejection fraction <35%, the 4-month mortality was 12%. However, in this same group, those with any depression at the time of AMI had a 4-month mortality of 50% (relative risk 4.1, p = 0.01). Among patients aged ≥65 years, the mortality according to BDI scale grouping 0 to 3, 4 to 9, and 10+ was 2.6%, 17.1%, and 23.3%, respectively (p <0.002). Highest mortality rates were observed in patients with most severe depressive symptoms. However, compared with those without depression, higher mortality was also observed at very low levels of depressive symptoms (BDI 4 to 9) not generally considered clinically significant and below the level usually considered predictive of increased post-AMI mortality.read more
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Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts.
Donna M. Fick,James W. Cooper,William E. Wade,Jennifer L. Waller,J. Ross Maclean,Mark H. Beers +5 more
TL;DR: The application of the Beers criteria and other tools for identifying potentially inappropriate medication use will continue to enable providers to plan interventions for decreasing both drug-related costs and overall costs and thus minimize drug- related problems.
Journal ArticleDOI
ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction
Elliott M. Antman,Daniel T. Anbe,Paul W. Armstrong,Eric R. Bates,Lee A. Green,Mary M. Hand,Judith S. Hochman,Harlan M. Krumholz,Frederick G. Kushner,Gervasio A. Lamas,Charles J. Mullany,Joseph P. Ornato,David L. Pearle,Michael A. Sloan,Sidney C. Smith,Joseph S. Alpert,Jeffrey L. Anderson,David P. Faxon,Valentin Fuster,Raymond J. Gibbons,Gabriel Gregoratos,Jonathan L. Halperin,Loren F. Hiratzka,Sharon A. Hunt,Alice K. Jacobs +24 more
TL;DR: This document was approved by the American College of Cardiology Foundation Board of Trustees on May 7, 2004 and by theAmerican Heart Association Science Advisory and Coordinating Committee on May 5, 2004.
Journal ArticleDOI
Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial.
Lisa F. Berkman,James A. Blumenthal,Matthew M. Burg,Robert M. Carney,Diane J. Catellier,Marie J. Cowan,Susan M. Czajkowski,Robert F. DeBusk,James D. Hosking,Allan S. Jaffe,Peter G. Kaufmann,Pamela H. Mitchell,James E. Norman,Lynda H. Powell,James M. Raczynski,Neil Schneiderman +15 more
TL;DR: The intervention improved depression and social isolation, although the relative improvement in the psychosocial intervention group compared with the usual care group was less than expected due to substantial improvement in usual care patients.
Journal ArticleDOI
Sertraline Treatment of Major Depression in Patients With Acute MI or Unstable Angina
Alexander H. Glassman,Christopher M. O'Connor,Robert M. Califf,Karl Swedberg,Peter J. Schwartz,J. Thomas Bigger,K. Ranga Rama Krishnan,Louis T. van Zyl,J. Robert Swenson,Mitchell S. Finkel,Charles Landau,Peter A. Shapiro,Carl J. Pepine,Jack Mardekian,Wilma Harrison +14 more
TL;DR: It is suggested that sertraline is a safe and effective treatment for recurrent depression in patients with recent MI or unstable angina and without other life-threatening medical conditions.
Journal ArticleDOI
Depression as a risk factor for mortality in patients with coronary heart disease: a meta-analysis.
TL;DR: Depressive symptoms and clinical depression have an unfavorable impact on mortality in CHD patients and depression has to be considered a relevant risk factor in patients with CHD.
References
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Journal ArticleDOI
Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation
TL;DR: A meta-analysis of the BDI's internal consistency estimates yielded a mean coefficient alpha of 0.86 for psychiatric patients and 0.81 for non-psychiatric subjects as mentioned in this paper.
Journal ArticleDOI
The Structured Clinical Interview for DSM-III-R (SCID). I: History, rationale, and description.
TL;DR: The history, rationale, and development of the Structured Clinical Interview for DSM-III-R (SCID) is described, which is a semistructured interview for making the major Axis I DSM- III-R diagnoses.
Journal ArticleDOI
What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes.
Jun Zhang,Kai F. Yu +1 more
TL;DR: This work proposes a simple method to approximate a risk ratio from the adjusted odds ratio and derive an estimate of an association or treatment effect that better represents the true relative risk.
Journal ArticleDOI
Sudden Cardiac Death
TL;DR: Total mortality, rather than classifications of cardiac and arrhythmic mortality, should be used as primary objectives for many outcome studies.
Journal ArticleDOI
Depression Following Myocardial Infarction: Impact on 6-Month Survival
TL;DR: Major depression in patients hospitalized following an MI is an independent risk factor for mortality at 6 months and its impact is at least equivalent to that of left ventricular dysfunction (Killip class) and history of previous MI.