Journal ArticleDOI
Experimental cerebral concussion
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This article is published in Brain.The article was published on 1941-09-01. It has received 519 citations till now.read more
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Journal ArticleDOI
Diffuse axonal injury and traumatic coma in the primate
Thomas A. Gennarelli,Lawrence E. Thibault,J H Adams,David I. Graham,C J Thompson,R. P. Marcincin +5 more
TL;DR: It is concluded that axonal damage produced by coronal head acceleration is a major cause of prolonged traumatic coma and its sequelae and is identical to that seen in severe head injury in humans.
Journal ArticleDOI
A controlled cortical impact model of traumatic brain injury in the rat.
TL;DR: The data demonstrate that controlled cortical impact in the rat reproduces many of the features observed in other experimental animal models, and allows independent control of many mechanical loading parameters associated with traumatic brain injury.
Journal ArticleDOI
Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury.
TL;DR: The data suggest that concussive brain injury causes a massive K+ flux which is likely to be related to an indiscriminate release of excitatory amino acids occurring immediately after brain injury.
Journal ArticleDOI
A fluid percussion model of experimental brain injury in the rat
C. E. Dixon,Bruce G. Lyeth,John T. Povlishock,Robert L. Findling,Robert J. Hamm,Anthony Marmarou,H. F. Young,Ronald L. Hayes +7 more
TL;DR: The data demonstrate that fluid percussion injury in the rat reproduces many of the features of head injury observed in other models and species, and could represent a useful experimental approach to studies of pathological changes similar to those seen in human head injury.