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Experimental examination of the quantitative imaging properties of optical diffraction tomography

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TLDR
In this article, a cross section of a transparent cylindrical object with known geometry and refractive index is reconstructed by optical diffraction tomography (ODT) using three liquids of different refractive indices to produce varying degrees of weak scattering.
Abstract
Optical diffraction tomography (ODT) is examined experimentally by reconstruction of a cross section of a transparent, cylindrical object with known geometry and refractive index. The object is immersed in three liquids of different refractive index to produce varying degrees of weak scattering. In each case the reconstructed size, shape, and refractive index are in good agreement with the known characteristics. This shows that quantitative images of transparent, cylindrical objects can be obtained by ODT. The images obtained from experimental data were also shown to be in good agreement with those obtained from computer-simulated data, thus verifying our computer simulations.

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Citations
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Journal ArticleDOI

New approach to optical diffraction tomography yielding a vector equation of diffraction tomography and a novel tomographic microscope.

TL;DR: A frequency‐space equation of diffraction tomography for the electric field vector is obtained within the first‐order Born approximation, using a simplified formalism resulting from using three‐dimensional spatial frequencies and replacing outgoing waves by linear combinations of homogeneous plane waves.
Journal ArticleDOI

Living specimen tomography by digital holographic microscopy: morphometry of testate amoeba

TL;DR: Morphometric measurements are extracted from the tomographic reconstructions, showing that the commonly used method for testate amoeba biovolume evaluation leads to systematic under evaluations by about 50%.
Journal ArticleDOI

Pulsed terahertz tomography

TL;DR: In this paper, the phase and amplitude of a terahertz time-domain spectroscopy (THz-TDS) pulse at each frequency can be determined by using a digital holography method.
Patent

High resolution device and method for imaging concealed objects within an obscuring medium

TL;DR: In this paper, a method and apparatus for imaging and identifying concealed objects within an obscuring medium using radiation (optical, photo-acoustic, ionizing, and/or acoustic) optimized for imaging (e.g. temporal properties, spectral bandwidth, directionality, polarization etc.).
Patent

Enhanced high resolution breast imaging device and method utilizing non-ionizing radiation of narrow spectral bandwidth

TL;DR: In this article, a method and apparatus for high resolution breast imaging using collimated non-ionizing acoustic radiation and electromagnetic radiation in the near ultraviolet, visible, infrared and microwave regions (i.e. "light") rather than ionizing x-radiation was presented.
References
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Journal ArticleDOI

A Filtered Backpropagation Algorithm for Diffraction Tomography

A. J. Devaney
- 01 Oct 1982 - 
TL;DR: The reconstruction algorithm is derived for parallel beam transmission computed tomography through two-dimensional structures in which diffraction of the insonifying beam must be taken into account and is applicable to diffraction tomography within either the first Born or Rytov approximations.
Journal ArticleDOI

Limitations of Imaging with First-Order Diffraction Tomography

TL;DR: In this article, the results of computer simulations used to determine the domains of applicability of the first-order Born and Rytov approximations in diffraction tomography for cross-sectional (or three-dimensional) imaging of biosystems are shown.
Journal ArticleDOI

A Computer Simulation Study of Diffraction Tomography

TL;DR: The filtered backprojection algorithm of X-ray tomography and the filtered backpropagation algorithm developed recently by the author for diffraction tomography are tested in computer simulations of ultrasonic tomography of two-dimensional objects for which the Rytov approximation is valid.
Journal ArticleDOI

Phase-retrieval and intensity-only reconstruction algorithms for optical diffraction tomography

TL;DR: In this paper, the authors compare two methods of reconstructing the complex index-of-refraction distribution of a scattering object from optical scattering data obtained in a set of scattering experiments employing incident monochromatic plane waves.
Journal ArticleDOI

Tomographic reconstruction from optical scattered intensities

TL;DR: In this article, a generalized tomographic reconstruction procedure is described for determining the complex-valued index-of-refraction distribution of a semitransparent, three-dimensional inhomogeneous object from observations of the far-field intensity patterns generated by the object in a sequence of scattering experiments.
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