Journal ArticleDOI
Ferrite-supported glutathione: an efficient, green nano-organocatalyst for the synthesis of pyran derivatives
TLDR
An efficient magnetically retrievable ferrite-supported glutathione nano-organocatalyst has been employed for the synthesis of a library of 2-amino-4H-pyran derivatives in aqueous media via a one-pot multicomponent reaction.Abstract:
An efficient magnetically retrievable ferrite-supported glutathione nano-organocatalyst has been employed for the synthesis of a library of 2-amino-4H-pyran derivatives in aqueous media via a one-pot multicomponent reaction. The highlight of this protocol lies in its operational simplicity, use of greener solvent, high yield within a very short period of time and reusability of the catalyst. This method provides an alternative greener approach for the synthesis of 2-amino-4H-pyran derivatives.read more
Citations
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Synthesis of functionalized chromene and spirochromenes using l-proline-melamine as highly efficient and recyclable homogeneous catalyst at room temperature
TL;DR: An efficient and recyclable homogeneous catalyst is developed using commercially cheap l -proline and melamine for the synthesis of chromenes and spirochromenes (spirooxindoles) via multicomponent reactions at room temperature as mentioned in this paper.
Journal ArticleDOI
Highly efficient magnetic Pd(0) nanoparticles stabilized by amine functionalized starch for organic transformations under mild conditions
TL;DR: In this paper, a novel and efficient palladium supported magnetic catalyst, [Pd@Fe 3 O 4 -NH 2 /Starch] was reported, which exhibited remarkable catalytic activity for the synthesis of functionalized secondary amines from aldehydes and nitroarenes via reductive amination.
Journal ArticleDOI
Novel ferrocene substituted benzimidazolium based ionic liquid immobilized on magnetite as an efficient nano-catalyst for the synthesis of pyran derivatives
TL;DR: In this article, a magnetically recoverable Fe3O4@SiO2-BenzIm-Fc[Cl]/NiCl2 nanoparticle was also synthesized using a simple chemical coprecipitation approach.
Journal ArticleDOI
4-Dialkylaminopyridine modified magnetic nanoparticles: as an efficient nano-organocatalyst for one-pot synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives in water
TL;DR: In this paper, a novel heterogeneous magnetic nano-organocatalyst was developed using immobilization of 4-dialkylaminopyridine moieties on Fe3O4 magnetic nanoparticles (MNP-DMAP).
Journal ArticleDOI
Starch functionalized magnetite nanoparticles: A green, biocatalyst for one-pot multicomponent synthesis of imidazopyrimidine derivatives in aqueous medium under ultrasound irradiation
Pratibha Verma,Shaili Pal,Swati Chauhan,A. N. Mishra,Indrajit Sinha,Sundaram Singh,Vandana Srivastava +6 more
TL;DR: An efficient and environmentally friendly one-pot multicomponent synthesis of biologically fascinating imidazopyrimidine derivatives by the reaction of aromatic aldehydes, active methylene compounds and 2-aminobenzimidazole under ultrasonic irradiation has been developed.
References
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Magnetic nanoparticles: Synthesis, protection, functionalization, and application
TL;DR: This review focuses on the synthesis, protection, functionalization, and application of magnetic nanoparticles, as well as the magnetic properties of nanostructured systems.
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Enamine-Based Organocatalysis with Proline and Diamines: The Development of Direct Catalytic Asymmetric Aldol, Mannich, Michael, and Diels−Alder Reactions
TL;DR: The contributions of this laboratory to converting enzymatic enamines, and in some cases imines, into a versatile catalytic asymmetric strategy powered by small organic molecules are summarized.
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Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
Jia-Lun Wang,Dongxiang Liu,ZhiJia Zhang,Simei Shan,Xiaobing Han,Srinivasa M. Srinivasula,Carlo M. Croce,Emad S. Alnemri,Ziwei Huang +8 more
TL;DR: The discovery of HA14-1, a small molecule and nonpeptidic ligand of a Bcl-2 surface pocket, provides a chemical probe to study B cl-2-regulated apoptotic pathways in vivo and could lead to the development of new therapeutic agents.
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A General Organocatalyst for Direct α-Functionalization of Aldehydes: Stereoselective C−C, C−N, C−F, C−Br, and C−S Bond-Forming Reactions. Scope and Mechanistic Insights
Johan Franzén,Mauro Marigo,Doris Fielenbach,Tobias C. Wabnitz,and Anne Kjærsgaard,Karl Anker Jørgensen +5 more
TL;DR: The development of a general organocatalyst for the alpha-functionalization of aldehydes, via an enamine intermediate, is presented and mechanistic insight into the reaction course applying nonlinear effect studies, kinetic resolution, and computational investigations leading to an understanding of the properties of the alpha,alpha-diarylprolinol silyl ether catalysts.
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Metal supported on dendronized magnetic nanoparticles: highly selective hydroformylation catalysts.
TL;DR: A method for homogenizing heterogeneous catalyst is described, based on growing polyaminoamido (PAMAM) dendrons on silica-coated magnetic nanoparticles, which are proven to be highly selective and reactive.