Filicidal ring-y chromosomes in d. melanogaster
TLDR
Experiments described here have unveiled a diverse class of genes that exert a maternal effect on the behavior during cleavage of these "filicidal" ring chromosomes.Abstract:
Ring-Y chromosomes are recovered infrequently from crosses of ring-Y-bearing males to females of certain strains (Oster 1964). Experiments described here have unveiled a diverse class of genes that exert a maternal effect on the behavior during cleavage of these "filicidal" ring chromosomes. Cytological observations of inviable embryos have revealed that the ring-Y chromosome causes gross disorganization of the cleavage nuclei. This inviability may be equivalent to the "dominant lethality" attributed to unstable ring-X chromosomes (Hinton 1955; Pasztor 1971). Mapping studies indicate that no single region of the normal Y is solely responsible for the unusual behavior of ring-Y chromosomes.read more
Citations
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Journal ArticleDOI
A Genetic Test of the Role of the Maternal Pronucleus in Wolbachia-Induced Cytoplasmic Incompatibility in Drosophila melanogaster
TL;DR: Using specific mutations in Drosophila melanogaster that produce androgenetic progeny, it is demonstrated that the Wolbachia-induced modification inhibits this type of development and argues against pronuclear asynchrony as the primary cause of CI lethality.
Journal ArticleDOI
A simple and rapid method for constructing ring-X chromosomes in Drosophila melanogaster
Mary M. Golic,Kent G. Golic +1 more
TL;DR: A method to construct ring-X chromosomes in Drosophila via I-CreI-mediated exchange in rDNA, and then rapidly diagnose the recovery of ring chromosomes via FLP-mediated sister chromatid exchange within the ring is described.
Journal ArticleDOI
Heterochromatin Position Effects on Circularized Sex Chromosomes Cause Filicidal Embryonic Lethality in Drosophila melanogaster
Patrick M. Ferree,Karina Gomez,Peter Rominger,Dagnie Howard,Hannah Kornfeld,Daniel A. Barbash +5 more
TL;DR: These experiments suggest that a large region of X-linked satellite DNA causes anaphase bridges and lethality when placed into a new heterochromatic environment within certain circularized X-Y chromosomes.
Journal ArticleDOI
Preferential Breakpoints in the Recovery of Broken Dicentric Chromosomes in Drosophila melanogaster
Hunter James Hill,Kent G. Golic +1 more
TL;DR: The results support the Laird hypothesis that intercalary heterochromatin can explain fragile sites in mitotic chromosomes, including fragile X.
Journal ArticleDOI
Mitotic misbehavior of a Drosophila melanogaster satellite in ring chromosomes: insights into intragenomic conflict among heterochromatic sequences
TL;DR: This finding suggests that ring misbehavior results from novel heterochromatin position effects on the 359-bp satellite, and similarities of this system to a satellite-based hybrid incompatibility and potential influences on genome evolution are discussed.
References
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Book
Non-Disjunction as Proof of the Chromosome Theory of Heredity
TL;DR: Page 15, table 1, column 4, for "158" read "138".
Journal ArticleDOI
The Behavior of an Unstable Ring Chromosome of Drosophila Melanogaster.
Journal ArticleDOI
The Genetic Consequences of Anaphase Bridge Formation in Drosophila
Journal ArticleDOI
The developmental potential of synchronized amphibian cell nuclei.
TL;DR: It is concluded that donor cell cycle phase does have an effect on nuclear transplantation success and donor nuclei from G1 cells have a restricted capacity to support development beyond the blastula stage.
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