Flavonoids as Ligands for Peroxisome Proliferator-Activated Receptor γ
Ayman M. Mahmoud
- Vol. 2, Iss: 4, pp 0-0
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The article was published on 2015-01-01 and is currently open access. It has received 2 citations till now. The article focuses on the topics: Peroxisome proliferator-activated receptor.read more
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Journal ArticleDOI
Anticancer activity and docking study of flavone derivatives as peroxisome proliferator-activated receptorγ inhibitors
K. B. Patel,Premlata Kumari +1 more
TL;DR: The anticancer activity of various flavone derivatives and their probable binding interaction with the peroxisome proliferator-activated receptorγ (PPARγ) protein associated with various cancers through docking are discussed to give an insight into the development of a potent anticancer agent.
Journal ArticleDOI
Investigation of Zinc Supplement Impact on the Serum Biochemical Parameters in Pulmonary Tuberculosis: A Double Blinded Placebo Control Trial.
Bahareh Zolfaghari,Mahboobeh Ghanbari,Hadis Musavi,Parizad Bavandpour Baghshahi,Mohammad Taghikhani,Fatemeh Pourfallah +5 more
TL;DR: In this article, the authors investigated whether zinc supplementation can increase the effects of anti-TB treatment or not, and found that zinc supplementation results in earlier sputum smear conversion in the micronutrient group during the first 6 weeks.
References
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Fat and beyond: the diverse biology of PPARgamma.
TL;DR: Recent advances in the understanding of the diverse biological actions of PPARgamma are reviewed with an eye toward the expanding therapeutic potential of PPargamma agonist drugs.
Journal ArticleDOI
Flavonoids: biosynthesis, biological functions, and biotechnological applications.
TL;DR: Different strategies and achievements through the genetic engineering of flavonoid biosynthesis with implication in the industry and the combinatorial biosynthesis in microorganisms by the reconstruction of the pathway to obtain high amounts of specific compounds are discussed.
Book ChapterDOI
Effect of plant flavonoids on immune and inflammatory cell function
TL;DR: A considerable body of evidence suggests that plant flavonoids may be health-promoting, disease-preventing dietary compounds.
Journal ArticleDOI
Structure and function of enzymes involved in the biosynthesis of phenylpropanoids
TL;DR: Atomic resolution insights into the architecture and mechanistic underpinnings of phenylpropanoid metabolizing enzymes contribute to the understanding of the emergence and on-going evolution of specialized phenyl Propanoid products, and underscore the molecular basis of metabolic biodiversity at the chemical level.
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Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells
Christopher K. Glass,Kaoru Saijo +1 more
TL;DR: Recent studies providing insights into the distinct mechanisms that enable nuclear receptors to antagonize pro-inflammatory programmes of gene expression in macrophages and T cells by altering the turnover or recruitment of co-repressors and co-activators in a gene-specific manner are reviewed.