Follow‐up study of thymomas with special reference to their clinical stages
TLDR
Seven of 13 patients treated by subtotal resection survived more than five years with postopertive radiotherapy, and the five‐year survival rates of each clinical stage were 92.6% in Stage I, 85.7% in stages II and III, and 50% in stage IV.Abstract:
Follow-up data were obtained for 96 cases of thymoma. The one-year survival rate was 84.3%, the three-year 77.1%, the five-year 74.1%, and the ten-year 57.1%. The five-year survival rate of total resection group was 88.9%; that of non-radically treated group was 44.4%. Clinical stages were defined: Stage I--macroscopically encapsulated and microscopically no capsular invasion; Stage II--1. macroscopic invasion into surrounding fatty tissue of mediastinal pleura, or 2. microscopic invasion into capsule; Stage III--macroscopic invasion into neighboring organ; Stage IVa--pleural or pericardial dissemination; Stage IVb--lymphogenous or hematogenous metastasis. Five-year survival rates of each clinical stage were 92.6% in Stage I, 85.7% in Stage II, 69.6% in Stage III, and 50% in Stage IV. Recurrence after total resection was found in six of 69 cases. Seven of 13 patients treated by subtotal resection survived more than five years with postoperative radiotherapy.read more
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The World Health Organization histologic classification system reflects the oncologic behavior of thymoma: a clinical study of 273 patients.
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References
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Journal ArticleDOI
Thymoma: a clinicopathologic study.
Journal ArticleDOI
Thymoma. A clinical and pathological study of 65 cases
TL;DR: A clinicopathologic study of 65 patients with thymomas found that syndromes, particularly myasthenia gravis and red cell hypoplasia, affected survival to an equal or greater extent than did the direct effects of the tumors.
Journal ArticleDOI
Thymomas: Clinicopathologic features, therapy, and prognosis
TL;DR: Clinopathologic features indicating a poor prognosis were a non‐encapsulated tumor of a predominantly epithelial cell type, superior vena caval syndrome, malignant pleural effusion, supraclavicular lymph node involvement, dysphagia, hoarseness, myasthenia gravis, erythroid hypoplasia, and hypogammaglobulinemia.
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