Journal ArticleDOI
Friedrich Wilhelm Serturner, the discoverer of morphine
TLDR
The life and accomplishments of Friedrich Wilhelm Serturner, the discoverer of morphine, are described.Abstract:
Describes the life and accomplishments of Friedrich Wilhelm Serturner, the discoverer of morphine.read more
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Journal ArticleDOI
Natural Products as a Foundation for Drug Discovery
TL;DR: The aim of this unit is to review current strategies and techniques that increase the value of natural products as a source for novel drug candidates.
Journal ArticleDOI
In the arms of Morpheus : the development of morphine for postoperative pain relief
TL;DR: Since its isolation from opium almost 200 yr ago, morphine remains the most widely used analgesic and the standard against which all new opioids for postoperative pain relief are compared.
Journal ArticleDOI
Mining genomes to illuminate the specialized chemistry of life
TL;DR: The rapid accumulation of genomic information has revealed that the metabolic capacity of virtually all organisms is vastly underappreciated as discussed by the authors, and genome mining technologies are accelerating metabolite discovery in all organisms, including protists, plants and animals.
Journal ArticleDOI
Natural products as lead compounds in drug discovery
TL;DR: The compounds derived from various NP sources have been a basis for the development of clinically important agents active against various diseases, including taxol, vinblastine, vincristine, and topotecan, which are important anticancer agents in widespread clinical use.
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