Journal ArticleDOI
Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder.
Hans C. Breiter,Scott L. Rauch,Kenneth K. Kwong,John R. Baker,Robert M. Weisskoff,David N. Kennedy,Adair Kendrick,T. L. Davis,Aiping Jiang,Mark S. Cohen,Chantal E. Stern,John W. Belliveau,Lee Baer,Richard L. O'Sullivan,Cary R. Savage,Michael A. Jenike,Bruce R. Rosen +16 more
TLDR
Results of functional magnetic resonance imaging were consistent with past studies of obsessive-compulsive disorder that used other functional neuroimaging modalities, however, paralimbic and limbic activations were more prominent in the present study.Abstract:
Background: The new technique of functional magnetic resonance imaging was used to investigate the mediating neuroanatomy of obsessive-compulsive disorder symptoms. Methods: Ten patients with obsessive-compulsive disorder and 5 normal subjects were studied via functional magnetic resonance imaging during control and provoked conditions. Data analysis entailed parametric and nonparametric statistical mapping. Results: Statistical maps (nonparametric;P Conclusions: Results of functional magnetic resonance imaging were consistent with past studies of obsessive-compulsive disorder that used other functional neuroimaging modalities. However, paralimbic and limbic activations were more prominent in the present study.read more
Citations
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Journal ArticleDOI
Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268
Journal ArticleDOI
Functional imaging of brain responses to pain. A review and meta-analysis (2000).
TL;DR: Data suggest that hemodynamic responses to pain reflect simultaneously the sensory, cognitive and affective dimensions of pain, and that the same structure may both respond to pain and participate in pain control.
Journal ArticleDOI
Effects of attention and emotion on face processing in the human brain: An event-related fMRI study
TL;DR: The authors used event-related fMRI to assess whether brain responses to fearful versus neutral faces are modulated by spatial attention, and found that right fusiform activity was greater for fearful than neutral faces, independently of the attention effect on this region.
Journal ArticleDOI
Response and Habituation of the Human Amygdala during Visual Processing of Facial Expression
Hans C. Breiter,Nancy L. Etcoff,Paul J. Whalen,William A Kennedy,Scott L. Rauch,Randy L. Buckner,Monica M. Strauss,Steven E. Hyman,Bruce R. Rosen +8 more
TL;DR: The human amygdala responds preferentially to emotionally valenced faces and rapidly habituates to them and is counterbalanced to happy versus neutral faces, suggesting a possible generalized response to emotions valenced stimuli.
Journal ArticleDOI
The functional neuroanatomy of emotion and affective style.
TL;DR: It is proposed that the PFC plays a crucial role in affective working memory and is most directly involved in the representation of elementary positive and negative emotional states while the dorsolateral PFC may be involved inThe representation of the goal states towards which these elementarypositive and negative states are directed.
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Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268
Journal ArticleDOI
The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability
Wayne K. Goodman,Lawrence H. Price,Steven A. Rasmussen,Carolyn M. Mazure,Roberta L. Fleischmann,Candy L. Hill,George R. Heninger,Dennis S. Charney +7 more
TL;DR: In a study involving four raters and 40 patients with obsessive-compulsive disorder at various stages of treatment, interrater reliability for the total Yale-Brown Scale score and each of the 10 individual items was excellent, with high degree of internal consistency among all item scores demonstrated with Cronbach's alpha coefficient.