Journal ArticleDOI
Furosemide in patients with heart failure: Shift in dose-response curves
TLDR
Patients with congestive heart failure had shifts in this curve and for a number of patients the configuration differed substantially from a sigmoid curve, suggesting that furosemide excretion rate was related to response.Abstract:
We studied 10 patients with congestive heart failure to assess the dynamics of their response to 40 mg of furosemide. Patients excreted less sodium than normal controls: 142 +/- 36 and 245 +/- 16 mEq/4 hr (p < 0.05). Patients delivered the same amount of furosemide into the urine--14.9 +/- 2.0 and 18.7 +/- 2.1 mg/4 hr (p < 0.20)--but the time course of delivery differed. Normal subjects had a sigmoid-shaped curve when furosemide excretion rate was related to response. All patients but one had shifts in this curve and for a number of patients the configuration differed substantially from a sigmoid curve.read more
Citations
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ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
Sharon A. Hunt,William T. Abraham,Marshall H. Chin,Arthur M. Feldman,Gary S. Francis,Theodore G. Ganiats,Mariell Jessup,Marvin A. Konstam,Donna Mancini,Keith Michl,John A. Oates,Peter S. Rahko,Marc A. Silver,Lynne W. Stevenson,Clyde W. Yancy,Elliott M. Antman,Sidney C. Smith,Cynthia D. Adams,Jeffrey L. Anderson,David P. Faxon,Valentin Fuster,Jonathan L. Halperin,Loren F. Hiratzka,Alice K. Jacobs,Rick A. Nishimura,Joseph P. Ornato,Richard L. Page,Barbara Riegel +27 more
TL;DR: This document summarizes current capabilities, research and operational priorities, and plans for further studies that were established at the 2015 USGS workshop on quantitative hazard assessments of earthquake-triggered landsliding and liquefaction.
Journal ArticleDOI
ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure).
TL;DR: The American College of Cardiology (ACC)/American Heart Association (AHA) Task Force on Practice Guidelines regularly reviews existing guidelines to determine when an update or full revision is needed.
Journal ArticleDOI
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in Collaboration With the International Society for Heart and Lung Transplantation
Sharon A. Hunt,William T. Abraham,Marshall H. Chin,Arthur M. Feldman,Gary S. Francis,Theodore G. Ganiats,Mariell Jessup,Marvin A. Konstam,Donna Mancini,Keith Michl,John A. Oates,Peter S. Rahko,Marc A. Silver,Lynne W. Stevenson,Clyde W. Yancy +14 more
TL;DR: Theodore G. Feldman, MD, PhD, FACC, FAHA, Chair as mentioned in this paper, Chair, Chair of FAHA 2015, 2016, 2017, 2018, 2019, 2019
Journal ArticleDOI
2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults
Mariell Jessup,William T. Abraham,Donald E. Casey,Arthur M. Feldman,Gary S. Francis,Theodore G. Ganiats,Marvin A. Konstam,Donna Mancini,Peter S. Rahko,Marc A. Silver,Lynne W. Stevenson,Clyde W. Yancy +11 more
TL;DR: The 2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and This information is current as of August 30, 2010 http://content.onlinejacc.org/cgi/content/full/53/15/1343 located on the World Wide Web at: The online version of this article, along with updated information and services, is
Journal ArticleDOI
Relationship between heart failure treatment and development of worsening renal function among hospitalized patients
Javed Butler,Daniel E. Forman,William T. Abraham,Stephen S. Gottlieb,Evan Loh,Barry M. Massie,Christopher M. O'Connor,Michael W. Rich,Lynne W. Stevenson,Yongfei Wang,James B. Young,Harlan M. Krumholz +11 more
TL;DR: Several medical strategies, including the use of CCBs and a higher dose of loop diuretics, but not ACE inhibitors, were associated with a higher risk of WRF, although assessment of inhospital diuresis was limited and WRF could not be explained by greater fluid loss in patients.
References
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The renin-angiotensin-aldosterone system in congestive failure in conscious dogs.
TL;DR: The renin-angiotensin-aldosterone system plays an essential role in the maintenance of blood pressure during the genesis of congestive failure; in the later stages, blood pressure is dependent upon the increase in plasma volume.
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An explanation for and experimental correction of the abnormal water diuresis in cirrhosis
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The Kidney in Heart Failure
TL;DR: The kidneys participate to a major extent in the pathogenesis of congestive heart failure and a complex alteration of homeostatic mechanisms results when the heart fails as a pump.
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Pharmacodynamic analysis of the furosemide-probenecid interaction in man.
TL;DR: Probenecid pretreatment in man increased the overall response to furosemide in contrast to animal studies in which probenecid decreased response by inhibiting proximal renal tubular secretion of furoSemide to its active site.
Journal ArticleDOI
Deranged Sodium Homeostasis in Cirrhosis
TL;DR: The author's purpose is to review the role of renal sodium handling in liver disease and the reappraisal of thinking with regard to this abnormality in the light of recent findings from several laboratories.