Journal ArticleDOI
Galloylpaeoniflorin, a new acylated monoterpene glucoside from paeony root.
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TLDR
A new acylated monoterpene glucoside, galloylpaeoniflorin, was isolated from Paeony root and the structure was determined by chemical and spectroscopic methods.Abstract:
A new acylated monoterpene glucoside, galloylpaeoniflorin, was isolated from Paeony root. The structure was determined by chemical and spectroscopic methods.read more
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Chemical profiling of Radix Paeoniae evaluated by ultra-performance liquid chromatography/photo-diode-array/quadrupole time-of-flight mass spectrometry.
Song-Lin Li,Jing-Zheng Song,Franky Fung Kei Choi,Chun-Feng Qiao,Yan Zhou,Quan-Bin Han,Hong-Xi Xu +6 more
TL;DR: It could be concluded that UPLC-PDA-QTOFMS based chemical profiling is a powerful approach for the global quality evaluation of Radix Paeoniae as well as other herbal medicines.
Journal ArticleDOI
Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-kappaB signaling pathways.
Irina Tsoy Nizamutdinova,Hwa Min Oh,Young Nam Min,Sun Hee Park,Min Joo Lee,Ju Sun Kim,Min Hye Yean,Sam Sik Kang,Yeong Shik Kim,Ki Churl Chang,Hye Jung Kim +10 more
TL;DR: Paeonol inhibited U937 monocyte adhesion to HUVECs stimulated by TNF-alpha, suggesting that it may inhibit the binding of monocytes to endothelium by regulating the production of critical adhesion molecules by T NF-alpha.
Journal ArticleDOI
Phytochemical and biological studies of paeoniaceae.
TL;DR: By Chun-Nian Hea, Yong Peng, Yao-Chun Zhang, Li-Jia Xua, Jing Gua, and Pei-Gen Xiao.
Journal ArticleDOI
6'-O-Galloylpaeoniflorin Attenuates Cerebral Ischemia Reperfusion-Induced Neuroinflammation and Oxidative Stress via PI3K/Akt/Nrf2 Activation.
TL;DR: GPF possesses neuroprotective effects against oxidative stress, inflammation, and apoptosis after ischemia-reperfusion insult via activation of the PI3K/Akt/Nrf2 pathway.
Journal ArticleDOI
Paeonol and paeoniflorin, the main active principles of Paeonia albiflora, protect the heart from myocardial ischemia/reperfusion injury in rats.
Irina Tsoy Nizamutdinova,Yong Chun Jin,Ju Sun Kim,Min Hye Yean,Sam Sik Kang,Yeong Shik Kim,Jae Heun Lee,Han Geuk Seo,Hye Jung Kim,Ki Churl Chang +9 more
TL;DR: It is shown that both PF and PN reduced myocardial damage in rat through protection from apoptosis, suggesting that Paeonia albiflora Pallas might be useful in treating myocardIAL infarction.
References
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Journal ArticleDOI
Chemical studies on the oriental plant drugs—XXXIII : The absolute structures of paeoniflorin, albiflorin, oxypaeoniflorin and benzoylpaeoniflorin isolated from chinese paeony root
TL;DR: The absolute structure of paeoniflorin, a major principle of Chinese Paeony root (Paonia albiflora Pallas (Paeoniaceae)) was established as I and as shown in Chart 2 by the X-ray analysis of a bromo derivative (VI) of product K2 acetate (V).
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