Gamut of cardiac manifestations and complications of COVID-19: a contemporary review.
TLDR
Cardiac MRI has detected and characterized myocardial injury, with changes compatible with other inflammatory cardiomyopathies, and accumulating data will provide insight regarding the longitudinal impact of COVID-19 infection on cardiovascular morbidity and mortality.Abstract:
COVID-19 has posed an extraordinary burden on health and the economy worldwide. Patients with cardiovascular diseases are more likely to have severe illness due to COVID-19 and are at increased risk for complications and mortality. We performed a narrative literature review to assess the burden of COVID-19 and cardiovascular morbidity and mortality. Myocardial injury has been reported in 20%-30% of patients hospitalized due to COVID-19 and is associated with a worse prognosis and high mortality (~50%-60%). Proposed mechanisms of myocardial injury include inflammation within the myocardium (due to direct viral infection or cytokine storm), endotheliitis, coronary vasculitis, myocarditis, demand ischemia, plaque destabilization and right ventricular failure. The right ventricle is particularly vulnerable to injury and failure in COVID-19-infected patients, given the hypoxic pulmonary vasoconstriction, pulmonary microthrombi or pulmonary embolism. Echocardiography is an effective and accessible tool to evaluate left and right ventricular functions and risk stratify patients with COVID-19 infection. Cardiac MRI has detected and characterized myocardial injury, with changes compatible with other inflammatory cardiomyopathies. The long-term consequences of these inflammatory changes are unknown, but accumulating data will provide insight regarding the longitudinal impact of COVID-19 infection on cardiovascular morbidity and mortality.read more
Citations
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Midterm functional sequelae and implications in rehabilitation after COVID-19: a cross-sectional study.
Alessio Baricich,Margherita Borg,Daria Cuneo,Emanuela Cadario,Danila Azzolina,Piero Emilio Balbo,Mattia Bellan,Patrizia Zeppegno,Mario Pirisi,Carlo Cisari +9 more
TL;DR: In this article, a cross-sectional study focused on mid-term functional outcomes evaluation in COVID-19 survivors was conducted to assess the physical performance at 3 to 6 months from hospital discharge.
Journal ArticleDOI
Cardiac abnormalities in athletes after SARS-CoV-2 infection: a systematic review.
Juliette C van Hattum,Jessica L Spies,S M Verwijs,Germaine C. Verwoert,R. Nils Planken,S. Matthijs Boekholdt,Maarten Groenink,Arjan Malekzadeh,Yigal M. Pinto,Arthur A.M. Wilde,Harald T. Jørstad +10 more
TL;DR: A systematic review on post-SARS-CoV-2 infection pericardial/myocardial manifestations in athletes is presented in this article, showing that athletes have an overall low risk of SARS CoV2 infection, arrhythmias and sudden cardiac arrest/sudden cardiac death.
Journal ArticleDOI
Clinical variants of myocardial involvement in COVID-19-positive patients: a cumulative experience of 2020.
TL;DR: In this article, the authors identified 90 cases of COVID-19 with myocardial involvement, mean age 52.9 ± 18.3 months, 54.5% males, 55 survived (61.1%), 20 died (22.2%), and in 15 (16.7%) the outcome was unknown at the time of publication.
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A Potential Role of the CD47/SIRPalpha Axis in COVID-19 Pathogenesis.
Katie-May McLaughlin,Denisa Bojkova,Joshua D. Kandler,Marco Bechtel,Philipp Reus,Trang T. Le,Florian Rothweiler,Julian U. G. Wagner,Andreas Weigert,Sandra Ciesek,Sandra Ciesek,Mark N. Wass,Martin Michaelis,Jindrich Cinatl +13 more
TL;DR: In this paper, the authors show that levels of CD47, which is known to mediate immune escape in cancer and virus-infected cells, are elevated in SARS-CoV-2-infect infected Caco-2 cells, Calu-3 cells, and air-liquid interface cultures of primary human bronchial epithelial cells.
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Recovery of functional fitness, lung function, and immune function in healthcare workers with nonsevere and severe COVID-19 at 13 months after discharge from the hospital: a prospective cohort study
Lijuan Xiong,Qian Li,Xiongjing Cao,Huangguo Xiong,Min Huang,Fengwen Yang,Da-Quan Meng,Mei Zhou,Yanzhao Zhang,Y. Fan,Liang V. Tang,Yang Jin,Jiahong Xia,Yu Hu +13 more
TL;DR: Wang et al. as mentioned in this paper evaluated the recovery of functional fitness, lung function, and immune function in healthcare workers with nonsevere and severe COVID-19 at 13 months after discharge from the hospital.
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