Gender differences in the prospective associations of self-reported sleep quality with biomarkers of systemic inflammation and coagulation: Findings from the Heart and Soul Study
Aric A. Prather,Elissa S. Epel,Beth E. Cohen,Beth E. Cohen,Thomas C. Neylan,Thomas C. Neylan,Mary A. Whooley +6 more
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TLDR
Investigation of cross-sectional and prospective associations of self-reported sleep quality with biomarkers of inflammation and coagulation implicated in coronary heart disease (CHD) and to explore whether these associations differed between men and women found poorer subjective sleep quality at baseline was prospectively associated with 5-year increases in IL-6.About:
This article is published in Journal of Psychiatric Research.The article was published on 2013-09-01 and is currently open access. It has received 80 citations till now. The article focuses on the topics: Heart disorder & C-reactive protein.read more
Figures
Table 4 Longitudinal results of regression analyses showing that poorer baseline PSQI subjective sleep quality predicts 5-year increases in IL-6, CRP, and fibrinogen in women but not men. 
Table 5 Longitudinal results of regression analyses showing that poorer baseline PSQI subjective independent of study covariates. 
Table 2 Cross-sectional results of linear regressions examining baseline and 5-year PSQI subjective sleep quality associations with baseline and 5-year levels of IL-6, CRP, and fibrinogen. Models adjusted for age, gender, ethnicity, education, BMI, and regular snoring. 
Table 3 Baseline characteristics stratified by gender. Values displayed as means (standard deviation) and percentages. 
Table 1 Sample characteristics at baseline and follow-up. Values displayed as means (standard deviation) or percentages.
Citations
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Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation
TL;DR: Global evidence linking sleep disturbance, sleep duration, and inflammation in adult humans is assessed and sleep disturbance and long sleep duration are associated with increases in markers of systemic inflammation.
Journal ArticleDOI
The Sleep-Immune Crosstalk in Health and Disease
TL;DR: The induction of a hormonal constellation that supports immune functions is one likely mechanism underlying the immune-supporting effects of sleep, and sleep appears to promote inflammatory homeostasis through effects on several inflammatory mediators, such as cytokines.
Journal ArticleDOI
Sleep and inflammation: partners in sickness and in health.
TL;DR: The current understanding of the relationship between sleep dynamics and host defence mechanisms is described, with a focus on cytokine responses, the neuroendocrine and autonomic pathways that connect sleep with the immune system and the role of inflammatory peptides in the homeostatic regulation of sleep.
Journal ArticleDOI
Sleep Health: Reciprocal Regulation of Sleep and Innate Immunity
Michael R. Irwin,Mark R. Opp +1 more
TL;DR: Interactions between sleep and inflammatory biology mechanisms underscore the implications of sleep disturbance for inflammatory disease risk, and provide a map to guide the development of treatments that modulate inflammation, improve sleep, and promote sleep health.
Journal ArticleDOI
Implications of sleep disturbance and inflammation for Alzheimer's disease dementia
TL;DR: A bidirectional relationship between sleep and Alzheimer's disease is supported by advances in understanding of sleep disturbance-induced increases in systemic inflammation, which can be viewed as an early event in the course of Alzheimer’s disease.
References
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Journal ArticleDOI
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
TL;DR: The CES-D scale as discussed by the authors is a short self-report scale designed to measure depressive symptomatology in the general population, which has been used in household interview surveys and in psychiatric settings.
Journal ArticleDOI
The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research.
TL;DR: The clinimetric and clinical properties of the PSQI suggest its utility both in psychiatric clinical practice and research activities.
Journal ArticleDOI
Atherosclerosis — An Inflammatory Disease
TL;DR: Atherosclerosis is an inflammatory disease as discussed by the authors, and it is a major cause of death in the United States, Europe, and much of Asia, despite changes in lifestyle and use of new pharmacologic approaches to lower plasma cholesterol concentrations.
Journal Article
Atherosclerosis is an Inflammatory Disease
光宏 横山,Russell Ross +1 more
TL;DR: Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations, cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.
Journal ArticleDOI
C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women
TL;DR: The addition of the measurement of C-reactive protein to screening based on lipid levels may provide an improved method of identifying persons at risk for cardiovascular events.