Journal ArticleDOI
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
TLDR
The 2023 Statistical Update as mentioned in this paper provides the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health.Abstract:
Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing. The 2023 Statistical Update is the product of a full year’s worth of effort in 2022 by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. The American Heart Association strives to further understand and help heal health problems inflicted by structural racism, a public health crisis that can significantly damage physical and mental health and perpetuate disparities in access to health care, education, income, housing, and several other factors vital to healthy lives. This year’s edition includes additional COVID-19 (coronavirus disease 2019) publications, as well as data on the monitoring and benefits of cardiovascular health in the population, with an enhanced focus on health equity across several key domains. Results: Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions. read more
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Journal ArticleDOI
Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management (Review)
Jianfeng He,Danyong Liu,Lixia Zhao,Dongcheng Zhou,Jianhui Rong,Liangqing Zhang,Zhengyuan Xia +6 more
TL;DR: The association between cell death-associated signaling pathways were elaborated, providing direction for investigation of novel targets in clinical treatment, and the mechanisms underlying MIRI were reviewed.
Journal ArticleDOI
2022 Guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the Management of Hypertension.
TL;DR: The guidelines of the Taiwan Society of Cardiology (TSOC) and the Taiwan Hypertension Society (THS) as discussed by the authors have been used to recommend the definition of hypertension as ≥ 130/80 mmHg.
Journal ArticleDOI
Cardiac fibroblasts secrete exosome microRNA to suppress cardiomyocyte pyroptosis in myocardial ischemia/reperfusion injury
TL;DR: In this paper , the authors used exosomes derived from cardiac fibroblasts (CFs) with overexpressed microRNA-133a to enhance the therapeutic outcomes for the MI/R injury.
Journal ArticleDOI
Clinical Trial Design Principles and Outcomes Definitions for Device-Based Therapies for Hypertension: A Consensus Document From the Hypertension Academic Research Consortium
TL;DR: The Hypertension Academic Research Consortium (HARC) document as discussed by the authors represents an integration of evolving evidence and consensus opinion among leading experts in cardiovascular medicine and hypertension research with regulatory perspectives on clinical trial design and methodology.
Journal ArticleDOI
Electrically conductive carbon‐based (bio)‐nanomaterials for cardiac tissue engineering
Negin Jalilinejad,Mohammad Rabiee,Nafiseh Baheiraei,Ramin Ghahremanzadeh,Reza Salarian,Navid Rabiee,Omid Akhavan,Payam Zarrintaj,Aleksander Hejna,Mohammad Reza Saeb,Ali Zarrabi,Esmaeel Sharifi,Sattar Yousefiasl,Ehsan Nazarzadeh Zare +13 more
TL;DR: In this paper , a review of the use of carbon-based nanoparticles in cardiac tissue engineering emphasizing their conductivity is presented, and the most commonly used conductive substrates comprising graphene, graphene oxide, carbon nanotubes, and carbon nanofibers in cardiac repair are studied.
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TL;DR: This study has demonstrated that careful use of a shared control group represents a safe and effective approach to GWA analyses of multiple disease phenotypes; generated a genome-wide genotype database for future studies of common diseases in the British population; and shown that, provided individuals with non-European ancestry are excluded, the extent of population stratification in theBritish population is generally modest.