High prevalence of hyposalivation in individuals with neurofibromatosis 1: a case-control study
Karin Soares Gonçalves Cunha,Rafaela Elvira Rozza-De-Menezes,Eloá Borges Luna,Lilian Machado De Sousa Almeida,Raquel Richelieu Lima De Andrade Pontes,Paula Nascimento Almeida,Letícia Vidaurre de Aguiar,Eliane Pedra Dias +7 more
TLDR
Hyposalivation may be a consequence of NF1, as occurs in other genetic diseases, and more studies are necessary to understand if there is and what is the relationship between NF1 and hyposalivation.Abstract:
Background
Neurofibromatosis type 1 (NF1) is one of the most common genetic diseases in humans and has widely variable expressivity. Oral manifestations are common, but there are no studies that investigated functional alterations in salivary glands in NF1. Our aim was to evaluate the salivary flow rate in NF1 individuals, comparing to a control group, and to investigate the possible causes and some consequences of salivary gland alteration.read more
Citations
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Journal ArticleDOI
Caries experience and salivary aspects in individuals with fragile X syndrome.
TL;DR: The experience of dental caries in individuals with FXS was correlated with salivary parameters, poor oral hygiene, lower socioeconomic status and an increased count of S. mutans in saliva.
Journal ArticleDOI
Age-dependent oral manifestations of neurofibromatosis type 1: a case–control study
TL;DR: In this article , the functional salivary analysis was performed to identify mutually activated pathways for NF1-associated oral complications, including periodontal destruction, salivial changes, and dental caries in NF1 patients.
Journal ArticleDOI
Craniomaxillofacial morphology alterations in children, adolescents and adults with neurofibromatosis 1: A cone beam computed tomography analysis of a Brazilian sample.
Eloá-Borges Luna,Maria-Elisa-Rangel Janini,Flávia Lima,Raquel-Richelieu-de Andrade Pontes,Fábio-Ribeiro Guedes,Mauro Geller,Licínio Esmeraldo da Silva,Alexandre-Trindade Motta,Karin Soares Gonçalves Cunha +8 more
TL;DR: Brazilian children, adolescents and adults with NF1 have short mandible, maxilla and skull base, and children and adolescents present mandibular retrusion.
Journal ArticleDOI
Oral Manifestations of Neurofibromatosis Type 1
Hafida Cherifi,Benjamin Fournier,Ariane Berdal,Blake McAlpin,Ishaï-Yaacov Sitbon,Bruno Gogly +5 more
TL;DR: The oral manifestations of neurofibromatosis type 1 are reviewed, illustrated by a patient followed in the center of rare diseases of the hospital Henri Mondor, clinical service in which the patient works.
References
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Journal Article
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