Open AccessJournal Article
HL-A Antigens from a Continuous Lymphoid Cell Line Derived from a Normal Donor: I. Solubilization and Serologic Characterization
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TLDR
Water soluble HL-A antigens isolated from a cultured human lymphocyte cell line derived from the peripheral blood of a normal donor inhibited cytotoxic reactions of monospecific anti-HL- A antisera in a pattern identical to that found upon direct and absorption typing of the donor's peripheral lymphocytes.Abstract:
Water soluble HL-A antigens isolated from a cultured human lymphocyte cell line derived from the peripheral blood of a normal donor inhibited cytotoxic reactions of monospecific anti-HL-A antisera in a pattern identical to that found upon direct and absorption typing of the donor's peripheral lymphocytes. The possibility of obtaining large quantities of cells from mass cultures now makes the chemical and biologic characterization of HL-A antigens a reality.read more
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Salt extraction of soluble HL-A antigens.
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Production of beta 2-microglobulin by normal and malignant human cell lines and peripheral lymphocytes.
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Evaluation of two sources of soluble HL-A antigens: platelets and serum.
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Cultured human lymphocytes.
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