Journal ArticleDOI
Human blood platelet monoamine oxidase.
G.G.S. Collins,M. Sandler +1 more
TLDR
The differences between the physicochemical properties of platelet MAO and isoenzymes from other anatomical sites suggests that the platelet enzyme is unlikely to provide a satisfactory index of in vivo activity in the whole organism.About:
This article is published in Biochemical Pharmacology.The article was published on 1971-02-01. It has received 105 citations till now. The article focuses on the topics: Monoamine oxidase B & Benzylamine Oxidase.read more
Citations
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Journal ArticleDOI
Reduced Monoamine Oxidase Activity in Blood Platelets from Schizophrenic Patients
TL;DR: Direct examination of cellular MAO in schizophrenic patients might be of interest and the evidence that MAO-inhibiting drugs may on occasion contribute to exacerbations of psychotic behaviour is suggested.
Journal ArticleDOI
Another look at the monoamine oxidases and the monoamine oxidase inhibitor drugs
Norton H. Neff,H.-Y.T. Yang +1 more
TL;DR: This chapter discusses the monoamine oxidases (MAO) and the MAO inhibitor drugs and it appears that MAO B is more sensitive to heat than MAO A and the thermostability of MAO preparations was dependent on the presence of phospholipid.
Journal ArticleDOI
Differences in Platelet Enzyme Activity between Alcoholics and Nonalcoholics
TL;DR: The inhibition of monoamine oxidase by ethanol was significantly higher in the platelets of alcoholics than in the controls, and the basal activity of adenylate cyclase was the same in platelets from the alcoholics and the controls.
Journal ArticleDOI
Substrate- and inhibitor-related characteristics of human platelet monoamine oxidase.
TL;DR: It is suggested that platelet MAO consists of essentially one distinguishable form of MAO which most closely resembles the MAO type B found in other tissues.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Estimation of the molecular weights of proteins by Sephadex gel-filtration.
TL;DR: The results are similar to those of previous studies, where the objective was to establish a cause-and-effect relationship, rather than a straightforward relationship between the number of cells and the content of the molecule.
Journal ArticleDOI
A sensitive and specific assay for the estimation of monoamine oxidase.
Journal ArticleDOI
The histochemical demonstration of monoamine oxidase activity by tetrazolium salts.
TL;DR: Localization of the formazan to autonomic ganglia and fibers, chief cells of the gastric fundus, mucosal epithelium of the duodenum and certain specific zones of the renal tubules by means of the tryptamine-tetrazolium technique was confirmed as indicating monoamine oxidase activity by identical localization using the hydrazone precipitation technique of Koelle and Valk.