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Hyperthermia in the treatment of cancer
S.B. Field,N.M. Bleehen +1 more
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This article is published in Cancer Treatment Reviews.The article was published on 1979-06-01. It has received 320 citations till now. The article focuses on the topics: Cancer.read more
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Recent Progress in Cancer Thermal Therapy Using Gold Nanoparticles
TL;DR: This work focuses on the developments and progress in nanoparticle design for photothermal cancer therapy since 2010, which includes in vitro and in vivo studies and the recent progression of gold nanoparticle photothermal therapy toward clinical cancer treatment.
Journal ArticleDOI
Targeted drug delivery by thermally responsive polymers.
TL;DR: In vivo fluorescent videomicroscopy and radiolabel distribution studies of ELP delivery to human tumors implanted in nude mice demonstrated that hyperthermic targeting of the thermally responsive ELP for 1 h provides a approximately two-fold increase in tumor localization compared to the same polypeptide without hyperthermia.
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Targeted hyperthermia using metal nanoparticles.
TL;DR: The emerging roles of nanoparticles, especially gold, in the hyperthermic treatment of cancer and the similarities of radiofrequency ablation and nanoparticle mediated cytotoxicity are discussed.
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Phototherapy of tumors
TL;DR: The precision possible for local treatment of solid tumors with lasers is greater than for almost any other techniques, but careful quantitative studies are needed to establish the appropriate treatment parameters in any particular situation.
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The current and potential role of hyperthermia in radiotherapy.
TL;DR: Current clinical experience strongly suggests that hyperthermia will become an important modality as an adjuvant to radiotherapy in the treatment of locally advanced solid tumors, and studies are underway to specifically elucidate the clinical relevance of thermotolerance and other biological issues.
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Journal ArticleDOI
The treatment of malignat tumors by repeated inoculations of erysipelas: with a report of ten original cases
Journal ArticleDOI
Cellular responses to combinations of hyperthermia and radiation.
TL;DR: The two principal rationales for applying hyperthermia in cancer therapy are that: the S phase, which is relatively radioresistant, is the most sensitive phase tohyperthermia, and can be selectively radiosensitized by combining hyperThermia with x-irradiation, and the cycling tumor cells in S phase could be killed by subjecting these cells toHyperthermia.
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Radiation Response of Mammalian Cells Grown in Culture: I. Repair of X-Ray Damage in Surviving Chinese Hamster Cells
M. M. Elkind,Harriet Sutton +1 more
TL;DR: A study was undertaken, using two-cell lines of the Chinese hamster propagated in vitro, to determine whether or not sublethal damage is heritsble, as might be expected if lethal damage is primarily genic.
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Selective heat sensitivity of cancer cells. Biochemical and clinical studies.
Renato Cavaliere,Enrico C. Ciocatto,Beppino C. Giovanella,Charles Heidelberger,Robert O. Johnson,Mario Margottini,Bruno Mondovi,Guido Moricca,A. Rossi-Fanelli +8 more
TL;DR: No conclusions about survivals can be drawn at present although four of seven patients with malignant melanomas treated only by heat perfusion are alive and well with functional limbs 28, 27, 11 and 7 months after treatment.
Journal ArticleDOI
Variation in Sensitivity to Heat Shock during the Cell-cycle of Chinese Hamster Cells in Vitro
Arthur Westra,W.C. Dewey +1 more
TL;DR: Heating of synchronous cells, obtained by the selective removal of mitotic cells from an asynchronous population, revealed that the mitotic and S phases were the most sensitive, primarily indicated by the smaller shoulders on the survival curves compared with the curve for cells heated in the resistant G1 phase.