Journal ArticleDOI
Hypothesis: does breast cancer originate in utero?
TLDR
The existing empirical data seem to be compatible with the hypothesis that increased concentrations of oestrogens in pregnancy increase the probability of future occurrence of breast cancer in daughters.About:
This article is published in The Lancet.The article was published on 1990-04-21. It has received 464 citations till now. The article focuses on the topics: Breast cancer & Cancer.read more
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A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives
Yoav Ben-Shlomo,Diana Kuh +1 more
BookDOI
A life course approach to chronic disease epidemiology
Diana Kuh,Yoav Ben-Shlomo +1 more
TL;DR: The Fetal growth and development: the role of nutrition and other factors and Should the authors intervene to improve fetal growth?
Journal ArticleDOI
The Danish National Birth Cohort - its background, structure and aim:
Jørn Olsen,Mads Melbye,Sjurdur F. Olsen,Thorkild I. A. Sørensen,Peter Aaby,Anne-Marie Nybo Andersen,Dorthe Taxbøl,Kit Dynnes Hansen,Mette Juhl,Tina Broby Schow,Henrik Toft Sørensen,Jente Andresen,Erik Lykke Mortensen,Annette Wind Olesen,Charlotte Søndergaard +14 more
TL;DR: The Danish National Birth Cohort (Better health for mother and child) was established, a large cohort of pregnant women with long-term follow-up of the offspring was the obvious choice because many of the exposures of interest cannot be reconstructed with sufficient validity back in time.
Journal ArticleDOI
Epigenetic epidemiology of the developmental origins hypothesis.
TL;DR: It is suggested that strategies for future human epidemiologic studies to identify causal associations between early exposures, long-term changes in epigenetic regulation, and disease, which may ultimately enable specific early-life interventions to improve human health, are suggested.
Journal ArticleDOI
The Swedish Twin Registry: a unique resource for clinical, epidemiological and genetic studies.
Paul Lichtenstein,U de Faire,Birgitta Floderus,Magnus Svartengren,Pia Svedberg,Nancy L. Pedersen,Nancy L. Pedersen +6 more
TL;DR: The Swedish Twin Registry is a unique resource for clinical, epidemiological and genetic studies (Review) and should be considered for further study.
References
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Journal ArticleDOI
Diet, nutrition, and cancer.
TL;DR: Studies conducted to date indicate that the modifying effect of diet and nutrition may be exerted through specific effects on 1) intestinal bacteria and substrates for bacterial metabolism, 2) microsomal mixed-function oxidase system, 3) endocrine system, 4) immunological system, 5) availability of metabolites for cell proliferation, and 6) rate of carcinogen transfer and duration of exposure to the carcinogen.
Journal ArticleDOI
The risk of breast cancer after estrogen and estrogen-progestin replacement.
TL;DR: In this cohort, long-term perimenopausal treatment with estrogens (or at least estradiol compounds) seems to be associated with a slightly increased risk of breast cancer, which is not prevented and may even be increased by the addition of progestins.
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The search for the causes of breast and colon cancer
TL;DR: Evidence is stronger for colon cancer, the occurrence of which may be reduced by diets with less animal fat and more fruit and vegetables, than for breast and colon cancers.
Journal ArticleDOI
Prenatal X-Ray Exposure and Childhood Cancer
TL;DR: In this article, a study was conducted to test the hypothesis that in utero exposure to x ray in diagnostic doses increases subsequent mortallty from neoplastic dlsease durlng chlldhood.