Journal ArticleDOI
Immune hemolytic anemia associated with drug therapy.
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TLDR
The most common drugs to cause DIIHA are anti-microbials, which are associated with drug-dependent antibodies, and the most common drug to cause AIHA is fludarabine.About:
This article is published in Blood Reviews.The article was published on 2010-07-01. It has received 186 citations till now. The article focuses on the topics: Immune Hemolytic Anemia & Autoimmune hemolytic anemia.read more
Citations
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Journal ArticleDOI
Long-term sequelae of drug reaction with eosinophilia and systemic symptoms: A retrospective cohort study from Taiwan
TL;DR: The sequelae of DRESS can be divided into 2 major types that appear to occur in different age groups: young patients tend to develop autoimmune diseases, whereas elderly patients are more vulnerable to end-organ failure.
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Diagnosis and classification of autoimmune hemolytic anemia.
TL;DR: In this article, the authors classified AIHA into warm, mixed or cold-reactive subtypes based on the optimal autoantibody-RBC reactivity temperatures and further subcategorized into idiopathic and secondary with the later being associated with a number of underlying infectious, neoplastic and autoimmune disorders.
Journal ArticleDOI
Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium
Annemarie Rosan Kreeftmeijer-Vegter,Perry J.J. van Genderen,Leo G. Visser,Wouter F W Bierman,Jan Clerinx,Cees K. W. van Veldhuizen,Peter J. de Vries +6 more
TL;DR: Data from the named patient programme demonstrate that IV artesunate is effective and well-tolerated in European travellers lacking immunity, however, increased attention needs to be paid to the possible development of haemolytic anaemia 2-3 weeks after start of treatment.
Journal ArticleDOI
Immune hemolytic anemia caused by drugs
TL;DR: DIIHA is often poorly investigated and many reports do not provide data to support the diagnosis, so it is important to exclude DIIHA in such patients as the only treatment needed is to discontinue the drug.
Journal ArticleDOI
Guidelines on the management of drug-induced immune and secondary autoimmune, haemolytic anaemia
TL;DR: Although recommendations are unchanged, an expanded version of this guideline is available as Appendix S2, and the Grading of Recommendations Assessment, Development and Evaluation nomenclature was used to evaluate levels of evidence and to assess the strength of recommendations.
References
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Journal ArticleDOI
Proportion of drug‐related serious rare blood dyscrasias: Estimates from the Berlin Case‐Control Surveillance Study
TL;DR: It is suggested that a substantial fraction of blood dyscrasias may be attributable to drug therapy, and the proportion of drug‐related cases using data from the ongoing Berlin Case‐Control Surveillance Study is estimated.
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Ex vivo antigen preparation for the serological detection of drug-dependent antibodies in immune haemolytic anaemias
TL;DR: It is concluded that the use of ex vivo antigens is of great importance in the serological evaluation of cases with suspected drug‐dependent immune haemolysis.
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Positive direct antiglobulin tests and haemolytic anaemia following therapy with beta-lactamase inhibitor containing drugs may be associated with nonimmunologic adsorption of protein onto red blood cells.
TL;DR: Patients' sera did not react with red blood cells in the presence of Unasyn or Timentin, but when drug‐treated RBCs were tested, patients'Sera and normal sera reacted equally by indirect antiglobulin test.
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Serological studies of piperacillin antibodies
TL;DR: In six cases of piperacillin‐induced IHA, reactivity with piperACillin‐ coated RBCs was not similar to reactivity of antipenicillin with penicillin‐coated R BCs.