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Improved Scoring System to Assess Adult Donors For Cadaver Renal Transplantation

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TLDR
The improved scoring system developed from a large population database provides a quantitative approach to evaluation of marginal kidneys and may improve allocation of these organs in cadaver renal transplantation.
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This article is published in American Journal of Transplantation.The article was published on 2003-06-01 and is currently open access. It has received 187 citations till now. The article focuses on the topics: Transplantation & Kidney transplantation.

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Journal ArticleDOI

A comprehensive risk quantification score for deceased donor kidneys: the kidney donor risk index.

TL;DR: The graded impact of KDRI on graft outcome makes it a useful decision-making tool at the time of the deceased donor kidney offer, and it is likely that there is a considerable overlap in the KDRI distribution by expanded and nonexpanded criteria donor classification.
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A systematic review of kidney transplantation from expanded criteria donors.

TL;DR: ECD kidneys have worse long-term survival than standard criteria donor kidneys and patients younger than 40 years or scheduled for kidney retransplantation should not receive an ECD kidney, based on the available evidence.
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Which renal transplant candidates should accept marginal kidneys in exchange for a shorter waiting time on dialysis

TL;DR: Older and frailer transplant candidates benefit from accepting lower quality organs early after ESRD, whereas younger and healthier patients benefit from receiving higher quality organs even with longer dialysis exposure.
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Factors influencing long-term outcome after kidney transplantation.

TL;DR: Although current immunosuppression regimes are highly efficient in preventing acute rejection, the burden of specific (diabetes, nephrotoxicity) and nonspecific side effects has significant negative long‐term consequences that may well be worse in the future because of the increasing ages of both donors and recipients.
References
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Journal ArticleDOI

Prediction of Creatinine Clearance from Serum Creatinine

Donald W. Cockcroft, +1 more
- 01 Jan 1976 - 
TL;DR: A formula has been developed to predict Creatinine clearance from serum creatinine (Scr) in adult males: Ccr = (140 – age) (wt kg)/72 × Scr (mg/100ml) (15% less i).
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Survival in Recipients of Marginal Cadaveric Donor Kidneys Compared with Other Recipients and Wait-Listed Transplant Candidates

TL;DR: It is concluded that transplantation of a marginal kidney is associated with a significant survival benefit when compared with maintenance dialysis and the average increase in life expectancy for MDK recipients compared with the WLD cohort was 5 yr, although this benefit varied from 3 to 10 yr depending on the recipient's characteristics.
Journal ArticleDOI

Biopsy of marginal donor kidneys: correlation of histologic findings with graft dysfunction.

TL;DR: Histopathological parameters present in donor biopsies can independently predict post-transplant graft function and implications for the pool of donor organs available for transplantation are discussed.
Journal Article

The UNOS OPTN Waiting List and Donor Registry: 1988-1996.

TL;DR: There were 49,233 registrations on the combined UNOS waiting list as of October 31, 1996, an increase of 207% over December 31, 1988 as discussed by the authors, of which 69% were waiting for kidney transplantation, and 14.6% were awaiting liver transplantation.
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