Journal ArticleDOI
In vitro inhibition of CYP2B1 monooxygenase by β-myrcene and other monoterpenoid compounds
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TLDR
The potent inhibitory effects on CYP4502B1 suggest that MYR, and other monoterpenes, interfere with the metabolism of xenobiotics which are substrates for this isoenzyme.About:
This article is published in Toxicology Letters.The article was published on 1997-06-16. It has received 133 citations till now. The article focuses on the topics: myr.read more
Citations
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Biological effects of essential oils - A review
TL;DR: Findings suggest that, at least in part, the encountered beneficial effects of essential oils are due to prooxidant effects on the cellular level.
Journal ArticleDOI
Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects
TL;DR: Particular focus will be placed on phytocannabinoid‐terpenoid interactions that could produce synergy with respect to treatment of pain, inflammation, depression, anxiety, addiction, epilepsy, cancer, fungal and bacterial infections (including methicillin‐resistant Staphylococcus aureus).
Journal ArticleDOI
Plant products as fumigants for stored-product insect control
S. Rajendran,V. Sriranjini +1 more
TL;DR: Although, in laboratory tests with adult insects, some of the plant compounds have shown insect toxicity comparable to methyl bromide or chloropicrin, their physical properties such as high molecular weight as well as high boiling point and very low vapour pressure are barriers for application in large-scale fumigations.
Review article Salvia for dementia therapy: review of pharmacological activity and pilot tolerability clinical trial
TL;DR: In a pilot open-label study involving oral administration of the essential oil to patients with AD, a significant increase in diastolic and systolic blood pressure was observed in two patients, however this may have been due primarily to preexisting hypertension and there were no abnormalities in other vital signs or blood samples during the trial period.
Journal ArticleDOI
Salvia for dementia therapy: review of pharmacological activity and pilot tolerability clinical trial.
TL;DR: Spanish sage extracts and constituents have demonstrated anticholinesterase, antioxidant, anti-inflammatory, oestrogenic and CNS depressant (sedative) effects all of which are currently relevant to the treatment of Alzheimer's disease (AD) as mentioned in this paper.
References
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Journal ArticleDOI
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
TL;DR: This assay is very reproducible and rapid with the dye binding process virtually complete in approximately 2 min with good color stability for 1 hr with little or no interference from cations such as sodium or potassium nor from carbohydrates such as sucrose.
Journal ArticleDOI
Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.
M.D. Burke,Stephanie Thompson,Clifford R. Elcombe,James R. Halpert,T Haaparanta,Richard T. Mayer +5 more
TL;DR: It is suggested that the use of some or all of these homologous phenoxazone ethers will provide both a simple routine test for the characterization of several types of inducing agents and a powerful tool for investigating the biochemical basis for cyt.
Book
Encyclopedia of Common Natural Ingredients: Used in Food, Drugs, and Cosmetics
Albert Y. Leung,Steven Foster +1 more
TL;DR: In this article, the authors present an overview of natural ingredients and their applications in the field of chemical engineering, including the following categories: Natural Ingredients, Chemical Index, and Chemical Index.
Journal ArticleDOI
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver.
TL;DR: Rat liver microsomal AROD results show that ratios between different alkoxyresorufin O-dealkylation (AROD) activities can be more useful than absolute values of single activities for identifying P450 forms.
Journal ArticleDOI
The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals.
Costas Ioannides,Dennis V. Parke +1 more
TL;DR: In this article, the Cytochrome P450 I Gene Family of Microsomal Hemoproteins and their Role in the Metabolic Activation of Chemicals are discussed. But they do not discuss the role of the P450 gene family of microsomal proteins.