Increased chain shortening of erucic acid in perfused heart from rats fed rapeseed oil
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The aim of the present work was to study cham shortening of [14C]erucrc acid m the perfused rat heart, and to see if the activity of this system was altered after prolonged feeding with rapeseed 011.About:
This article is published in FEBS Letters.The article was published on 1979-01-01 and is currently open access. It has received 23 citations till now. The article focuses on the topics: Erucic acid & Rapeseed.read more
Citations
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Journal ArticleDOI
Peroxisome proliferators and peroxisome proliferator activated receptors (PPARs) as regulators of lipid metabolism
Norbert Latruffe,Joseph Vamecq +1 more
TL;DR: The reader will be led to conclude that the discovery of PPARs and related gene activation through peroxisome proliferator responsive element (PPRE) makes PP induction one of the most illustrative examples of control that occurs in lipid metabolism.
Journal ArticleDOI
Metabolism of very long-chain monounsaturated fatty acids (22:1) and the adaptation to their presence in the diet.
TL;DR: It is suggested that CoA esters that are poorly oxidized by the mitochondria (e.g., esters of erucic acid, of some fatty acids with trans double bonds, and of clofibric acid) may trigger the adaptation to their presence in the diet.
Journal ArticleDOI
Erucic acid in feed and food
Helle Katrine Knutsen,Jan Alexander,Lars Barregård,Margherita Bignami,Beat Johannes Brüschweiler,Sandra Ceccatelli,Michael Dinovi,Lutz Edler,Bettina Grasl-Kraupp,Christer Hogstrand,Laurentius Hoogenboom,Carlo Nebbia,Isabelle P Oswald,Annette Petersen,Martin Rose,Alain-Claude Roudot,Tanja Schwerdtle,Günter Vollmer,Heather M. Wallace,Bruce Cottrill,Eugenia Dogliotti,Juha Laakso,Manfred Metzler,Leonardo Velasco,Katleen Baert,Jose Ángel Gómez Ruiz,Enikő Varga,Barbara Dörr,Rita Sousa,Christiane Vleminckx +29 more
TL;DR: In this paper, a tolerable daily intake (TDI) of 7 mg/kg body weight (bw) per day for erucic acid was established, based on a no observed adverse effect level of 0.7 g/kg bw per day.
Journal ArticleDOI
PEROXISOMAL βT‐OXIDATION OF LONG FATTY ACIDS: EFFECTS OF HIGH FAT DIETS*
TL;DR: The finding that oxidation of erucoyl carnitine by rat liver mitochondrial from clofibrate-treated rats was not markedly different from the rate obtained with control mitochondria, while oxidation of [14-'4C]erucate by hepatocytes isolated from cl ofibrates treated rats was markedly increased suggested that a nonmitochondrial process might be significant for cellular oxidation of C,,,-fatty acids.
Journal ArticleDOI
Stimulation of microperoxisomal β-oxidation in rat heart by high-fat diets
Jon Norseth,Magny S. Thomassen +1 more
TL;DR: In this paper, the effect of microperoxisomal beta-oxidation of the fatty acid composition of the dietary oils was investigated, and it was concluded that the heart plays an important part in the adaptation process.
References
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The effect of (-)carnitine on the metabolism of palmitate in liver cells isolated from fasted and refed rats.
TL;DR: Observations seen together suggest that both the relative activities of carnitine palmityltransferase and glycerophosphate acyl transferase and variations in the concentration of Carnival can have directing effects on the metabolic fate of fatty acids in the liver.
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Cardiac Lipid Changes in Rats Fed Oils Containing Long-Chain Fatty Acids
TL;DR: In this paper, the composition of the cardiac fatty acids and the histopathology in rats receiving oil as 40% of calories were studied after 3, 7, 14 and 28 days.
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The effects of clofibrate feeding on the metabolism of palmitate and erucate in isolated hepatocytes.
TL;DR: The isolated mitochondrial fraction from clofibrate-fed rats showed an increased capacity for oxidation of short-chain acylcarnitines (including acetylc Carnitine), while the oxidation of palmitoyl- and erucoylcarnitine showed little change.
Journal ArticleDOI
Chain shortening of erucic acid in isolated liver cells
TL;DR: The metabolism of erucic Acid in isolated liver cells has been studied and it is shown that part of the injected radioactivity is recovered in shorter monounsaturated fatty acids, particularly in oleic acid in liver.
Journal ArticleDOI
Erucic acid oxidation by beating heart cells in culture.
A. Pinson,P. Padieu +1 more
TL;DR: In the present work, oxidation of erucic acid by beating heart cells in culture has been studied to determine whether differentiated cultured cardiac cells in a tissue-like structure, are able themselves to oxidize erUCic acid and whether transformation is an essential step prior to oxidation.